Unit Guide

General Information

Unit convenor and teaching staff	Unit convenor and teaching staff Lecturer/ Unit Convener Abidali Mohamedali abidali.mohamedali@mq.edu.au Contact via 9850 9292 CBMS Level 1, F7B 119 TBA Lecturer Robert Willows robert.willows@mq.edu.au Contact via abidali.mohamedali@mq.edu.au E8A-203 TBA
Credit points	Credit points 3
Prerequisites	Prerequisites CBMS223 and CBMS224
Corequisites	Corequisites
Co-badged status	Co-badged status CBMS737 and CBMS837
Unit description	Unit description Biochemistry and cell biology are central to our understanding of medicine and biotechnology. Advances in these fields are dependent on an advanced understanding of the molecular basis of diverse cellular processes. This unit links important biochemical processes to functions and properties of eukaryotic cells. We explore advanced concepts including: enzyme function, properties of membranes, signal transduction, protein trafficking and transport, and protein turnover. These are linked to whole cell behaviours such as cell division and differentiation, programmed cell death, and general responses to external stimuli. Practical work complements lecture material and provides experience with a broad range of current techniques used in research and industry. Laboratory techniques used include analysis of signalling cascades, spectrophotometry, and fluorescence and light microscopy.

Important Academic Dates

Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates

Learning Outcomes

On successful completion of this unit, you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;
Contribute to the generation of new data and where appropriate entries in scientific databases.

General Assessment Information

Please refer to the Macquarie University Assessment policy regarding submission of assignments, plagarism, extensions, late submissions etc.

Assessment Tasks

Name	Weighting	Due
Practical Reports	15%	iLearn schedule/consult staff
Introduction and Methods	5%	Week 6
Post Lecture Study questions	0%	Weekly
Mid-Semester Exam	10%	Week 7
Human Cell Atlas Assignment	10%	Week 9
Hot Topics Seminar	10%	Practicals (Week 12-13)
Final Report	10%	Week 13
Final Examination	40%	University Examination Period

Practical Reports

Due: iLearn schedule/consult staff
Weighting: 15%

Practical reports will be due only for P2 and P3 (Hard copies to be submitted to the SCIENCE CENTRE) - All other practicals will be evaluated by a series of reflections post practical on iLEARN due one week from the practical date.

On successful completion you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;

Introduction and Methods

Due: Week 6
Weighting: 5%

An introduction and methods section is the first part of the final report to be submitted at the end of the semester. Feedback will be given which will improve the final report so it is essential that students submit this for marking.

On successful completion you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;

Post Lecture Study questions

Due: Weekly
Weighting: 0%

This involves a series of questions after every lecture to help you study. Submitting answers to these questions can earn students up to 3% bonus points.

On successful completion you will be able to:

Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;

Mid-Semester Exam

Due: Week 7
Weighting: 10%

There will be a 60 min exam (10% total assessment) held in the practical class of Week 7 (i.e., FRIDAY 11th September from 1.05 pm sharp). This will cover all materials and textbook reading associated with lectures 1-14. This is designed to give you specific feedback on your understanding of the topics up to this stage to assist you in your further study of the unit.

On successful completion you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Define the major biological systems and control points involved in a range of fundamental cell processes;

Human Cell Atlas Assignment

Due: Week 9
Weighting: 10%

Prepare an illustrated one (1) page summary of the biochemistry and cell biology of one (1) of the ~230 known human cell types for entry into the CBMS337 Macquarie Human Cell Atlas database. Additional submissions will get bonus marks up to 5% (2.5% for each additional submission up to a Maximum of 5%)

On successful completion you will be able to:

Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Hot Topics Seminar

Due: Practicals (Week 12-13)
Weighting: 10%

Prepare an individual PowerPoint presentation/seminar on a "hot topic" in molecular cell biology/biochemistry (List will be provided on iLEARN but students can suggest their own for approval). 3% will be allocated by your peers (averaged) and 7% by the staff.

On successful completion you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;

Final Report

Due: Week 13
Weighting: 10%

This report will be a cumulative scientific report (of P4-6) written in the form of a peer reviewed journal article. Submission will follow the international scientific journal PLoS ONE guidelines http://journals.plos.org/plosone/s/submission-guidelines. The style, formatting, layout, etc. MUST conform to this journal. Marking Criteria will be available on iLEARN.

On successful completion you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Final Examination

Due: University Examination Period
Weighting: 40%

The final exam (40% total assessment) will be 3hr in length with 10min reading time. It is designed to address specific understanding of topics presented in all of the lectures, practicals and peer-assisted leaning exercises and to show that the knowledge you have obtained can be applied to new problems.

On successful completion you will be able to:

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.

Delivery and Resources

Objective of the unit

To integrate cell biology and biochemistry components of the course seamlessly to offer a basic understanding of cellular functions, interactions, signalling and properties. This culminates in a demonstration of cell function in cancer.

Classes

Timetable: Please check https://timetables.mq.edu.au/2012/default.aspx for the official timetable of the unit.

Required and Recommended Texts and/or Materials

Prescribed Texts:

B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter (2015) "Molecular Biology of the Cell" (6^th Edition), ISBN 978-0-8153-4432-3. Available at the Co-op and a few copies for reference in the library.

Your lectures will cover the generic parts of each chapter and you are strongly advised to read and understand the reminder of each Alberts et al., chapter as referred to in the lecture outline. This book is an absolute essential item for your future in any aspect of molecular and cellular biology.

CBMS337 lecture notes can be obtained from the CBMS337 unit web site.

Further reading material is also available in the library:

R. Garrett & C. Grisham (2008) "Biochemistry" (4^th or earlier editions), Or any good Biochemistry textbook.

Technology Used and Required

You are expected to access the unit iLearn web site on a frequent basis and to download all necessary pdf files. To access the unit web site, if you have off-campus Internet access, simply start your web browser and proceed as above for logging in. On-campus wireless access is also available. If you do not have your own computer you may wish to access the CBMS337 web resources on campus using the computers in the Library.

To view the lecture notes and other pdf files on the website, you will require Adobe Acrobat Reader Version 9 or later to be installed on your computer. Acrobat Reader can be downloaded from the Adobe website http://get.adobe.com/uk/reader/. If you are using the computers in the library, then Acrobat has already been installed.

We will also be using Lecture Tools (from iLEARN) and therefore you will be required to bring your laptop,tablet,smartphone to the lectures.

Please note information may also be sent by email to your student email account so please look at your student email account on a frequent basis.

Unit Web Page

The web page for this unit is at Macquarie's new learning management system website: http://ilearn.mq.edu.au

You are expected to access the unit web site frequently (i.e., almost daily). This site contains important information including lecture notes (that you will be expected to access (via lecture tools) in class), mid-semester exams and/or assignment.

Logging In: Type in the URL http://ilearn.mq.edu.au and find CBMS3376/837/737. Your username is your Macquarie Student ID Number (MQID), which is an 8 digit number found on your student card. The password is your myMQ Student Portal password. This will be the original MQID password (2 random characters followed by your date of birth in ddmmyy format) that was sent to you on enrolment, unless you have already changed your password in the myMQ Student Portal. If you experience difficulties in getting your reprint or your password, please contact the StudentIT Desk (ph: 9850 6500).

Teaching and Learning Strategy

CBMS337 is a 3-credit point half-year unit and will require an average of 9 hours of work per week (contact hours plus self-study time). For students with “weaker” biochemistry backgrounds, more time than the 9 hours per week will probably be necessary to perform satisfactorily in this unit.

CBMS337 consists of 2 hours of lectures and a 3 hour laboratory class every week. The unit is designed to allow you to develop an understanding of biochemistry and cell biology and the practical skills to undertake experiments in this field in an efficient and safe manner. The lecture material and laboratories complement each other and have been developed to increase your understanding of the topics so you can achieve the learning outcomes.

The purpose of practicals will be to develop higher level critical thinking skills in students and teach contemporary methods in cell studies and biochemistry.

The Experiments are designed with REAL samples (HCT116 CRC cell line) resulting in an eventual publication of the results in a peer reviewed journal.
Will focus on collaborative work, critical thinking and methods development.

The unit coordinator’s expectation is that you will:

· Attend all interactive lectures. If you cannot attend a lecture, you are expected to listen to the iLecture as soon as possible after it is made available.

· Demonstrate reasonable competence in all laboratory preparation exercises and attend each laboratory class/tutorial.

· Perform satisfactorily in the final exam and all other assessments.

· Spend an average of no less than 3 hours per week of private study in addition to direct contact.

If you prepare and attend all components of the unit and work consistently/continuously throughout the semester, you should be able to develop a strong understanding of biochemistry and cell biology and how it operates in the context of molecular cell biology.

Students who “memorise” just before final exams typically do poorly in this unit.

You are expected to use the lecture materials in the lectures (or bring them) so you can spend most of the time listening rather than transcribing. The lectures are interactive and you will be expected to have input in polls and discussions. Do not assume notes or iLectures are in any way a suitable substitute for attending lectures – lecturers put an effort into making the lectures up to date and relevant, whilst textbooks cannot not cover all examples or the latest research. Students historically fall behind and perform poorly if they do not attend lectures.

Learning is an active process, and as such you must engage with the material. This means downloading and reading lecture notes and relevant sections of the textbook (and beyond) before and after lectures are strongly recommended.

· The mid-semester exam will be run in a practical class.

· Laboratory practical classes are designed to develop basic laboratory skills, general safety practices and critical and analytical thought. In-lab and post-lab work are designed to allow you to appropriately record experimental observations and calculations in a detailed and accurate manner and assess your understanding of the theory behind experiments.

Unit Schedule

CBMS337 Biochemistry & Cell Biology 2015 Lecture Plan , subject to minor changes

Unit Coordinator: Dr. Abidali Mohamedali (AM) Lecturers: A/Prof Rob Willows (RW), A/Prof Mark Molloy (MM) and Professor Nicki Packer (NP)

Monday: E3A 133 Collaborative Forum (1pm-2pm) and Tuesday E3A130 (10am-11am)

Day	Lecture	Week	Monday	Lecturer	Lecture Title	Objectives
Mon	1	1	27-Jul	AM	Introduction	Universal Features of cells, diversity/similarity of genomes
Tue	2	1	28-Jul	RW	Cell Chemistry/ Bioenergetics 1	Enzyme Kinetics
Mon	3	2	3-Aug	RW	Cell Chemistry/ Bioenergetics 2	Enzyme Kinetics
Tue	4	2	4-Aug	RW	Cell Chemistry/ Bioenergetics 3	Enzyme kinetics and regulation
Mon	5	3	10-Aug	RW	Biochemisty core	Evolution of Biochemical Pathways
Tue	6	3	11-Aug	RW	Protein function methods	Overview of methods of detecting interactions/function /Mutation analysis(Y2H, Biacore, MS etc)
Mon	7	4	17-Aug	AM	Mathematical analysis of Cell functions	Modelling cellular reactions, modelling interactions, differential equations predict steady state, Combinatorial control etc.
Tue	8	4	18-Aug	MM	Studying cells in culture	Overview of Common methods of cell culture, hybridoma , transfection, Protein expression
Mon	9	5	24-Aug	AM	Protein Function	Antibody binding, complex formation, phosphorylation, Ubiquitination, network of interactions
Tue	10	5	25-Aug	AM	Membrane transport	Principles of Membrane transport, Transporters (ATP Driven pumps, ATPase pumps, Na/K pumps etc.)
Mon	11	6	31-Aug	AM	Electrical Properties of Membranes	Electrical transport, Action potentials, mechano receptors, Ca ion transport, neuronal functions
Tue	12	6	1-Sep	NP	Intracellular compartments /protein sorting 1	Principles of compartmentalisation, Nuclear transport, transport to mitochondria and chloroplasts
Mon	13	7	7-Sep	NP	Intracellular compartments /protein sorting 2	Endoplasmic reticulum, protein folding, glycosylation , GPI anchors, membrane proteins
Tue	14	7	8-Sep	AM	Endo/exocytosis 1	Molecular mechanisms of membrane transport ER>Golgi transport,
MID SEMESTER BREAK
Mon	15	9	28-Sep	AM	Endo/Exocytosis 2	Trans Golgi Network transport to lysosome, Endocytosis and Exocytosis
Tue	16	9	29-Sep	AM	Cell Signalling 1	Principles of Cell Signalling
Mon		10	5-Oct	Labour Day
Tue	17	10	6-Oct	AM	Cell Signalling 2	G=Protein coupled receptor signalling
Mon	18	11	12-Oct	AM	Cell Signalling 3	Enzyme Coupled Receptor Signalling and alternative signalling routes
Tue	19	11	13-Oct	AM	Cytoskeleton 1	Actins and Myosin
Mon	20	12	19-Oct	AM	Cytoskeleton 2	Microtubules and IFilaments
Tue	21	12	20-Oct	AM	Cell Junctions	Cell-cell junctions, Cell-Matrix juctions
Mon	22	13	26-Oct	AM	Extracellular Matrix	ECM, nature and function
Tue	23	13	27-Oct	MM	Cancer 1
Mon	24	14	2-Nov	MM	Cancer 2
Tue	25	14	3-Nov	AM	Revision Lecture

CBMS337/837/737 Biochemistry & Cell Biology 2015 Practical Session Plan

Practical Demonstrator: A/Prof Rob Willows + Abidali Mohamedali + Other demonstrators

Fridays 10am-1pm E3A130 and 2pm-5pm E3A130 (only if required)

Week	Practical	Day	Practical Schedule	Practical Report Schedule Due Dates
1	P1	31st July	Methods Development
2	P2	7th Aug	Enzyme kinetics - Muscle pyruvate kinase Day 1
3	P3	14th Aug	Enzyme kinetics - Muscle pyruvate kinase Day 2
4	P4	21st Aug	Enzyme inhibition - Yeast hexokinase	Prac combined (P2+P3) Report
5	P5	28th Aug	Western blotting	P4 Report Due
6	P6	4th Sept	Western Blotting/ HPLC Demo	Prac 5 Reflections
7	P7	11th Sept	Mid Sem Exam	Prac 6 Reflections

9	P8	2nd Oct.	Immuno Flouresence/Biacore Demo
10	P9	9th Oct.	Immuno Flouresence/Microscopy	Prac 8 Questions
11	P10	16th Oct.	FACS	Prac 9- Questions
12	P11	23rd Oct.	Hot Topics seminar	Prac 10- Questions
13	P12	30th Oct.	Hot Topics seminar

Lecture & Practical timetable subject to change

Policies and Procedures

Macquarie University policies and procedures are accessible from Policy Central. Students should be aware of the following policies in particular with regard to Learning and Teaching:

Academic Honesty Policy http://mq.edu.au/policy/docs/academic_honesty/policy.html

Assessment Policy http://mq.edu.au/policy/docs/assessment/policy.html

Grading Policy http://mq.edu.au/policy/docs/grading/policy.html

Grade Appeal Policy http://mq.edu.au/policy/docs/gradeappeal/policy.html

Grievance Management Policy http://mq.edu.au/policy/docs/grievance_management/policy.html

Disruption to Studies Policy http://www.mq.edu.au/policy/docs/disruption_studies/policy.html The Disruption to Studies Policy is effective from March 3 2014 and replaces the Special Consideration Policy.

In addition, a number of other policies can be found in the Learning and Teaching Category of Policy Central.

Student Code of Conduct

Macquarie University students have a responsibility to be familiar with the Student Code of Conduct: https://students.mq.edu.au/support/student_conduct/

Results

Results shown in iLearn, or released directly by your Unit Convenor, are not confirmed as they are subject to final approval by the University. Once approved, final results will be sent to your student email address and will be made available in eStudent. For more information visit ask.mq.edu.au.

Student Support

Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/

Learning Skills

Learning Skills (mq.edu.au/learningskills) provides academic writing resources and study strategies to improve your marks and take control of your study.

Student Services and Support

Students with a disability are encouraged to contact the Disability Service who can provide appropriate help with any issues that arise during their studies.

Student Enquiries

For all student enquiries, visit Student Connect at ask.mq.edu.au

IT Help

For help with University computer systems and technology, visit http://informatics.mq.edu.au/help/.

When using the University's IT, you must adhere to the Acceptable Use Policy. The policy applies to all who connect to the MQ network including students.

Graduate Capabilities

Creative and Innovative

Our graduates will also be capable of creative thinking and of creating knowledge. They will be imaginative and open to experience and capable of innovation at work and in the community. We want them to be engaged in applying their critical, creative thinking.

This graduate capability is supported by:

Learning outcomes

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Practical Reports
Introduction and Methods
Mid-Semester Exam
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report
Final Examination

Capable of Professional and Personal Judgement and Initiative

We want our graduates to have emotional intelligence and sound interpersonal skills and to demonstrate discernment and common sense in their professional and personal judgement. They will exercise initiative as needed. They will be capable of risk assessment, and be able to handle ambiguity and complexity, enabling them to be adaptable in diverse and changing environments.

This graduate capability is supported by:

Learning outcomes

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;

Assessment tasks

Practical Reports
Mid-Semester Exam
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report
Final Examination

Commitment to Continuous Learning

Our graduates will have enquiring minds and a literate curiosity which will lead them to pursue knowledge for its own sake. They will continue to pursue learning in their careers and as they participate in the world. They will be capable of reflecting on their experiences and relationships with others and the environment, learning from them, and growing - personally, professionally and socially.

This graduate capability is supported by:

Learning outcomes

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Practical Reports
Post Lecture Study questions
Mid-Semester Exam
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report
Final Examination

Discipline Specific Knowledge and Skills

Our graduates will take with them the intellectual development, depth and breadth of knowledge, scholarly understanding, and specific subject content in their chosen fields to make them competent and confident in their subject or profession. They will be able to demonstrate, where relevant, professional technical competence and meet professional standards. They will be able to articulate the structure of knowledge of their discipline, be able to adapt discipline-specific knowledge to novel situations, and be able to contribute from their discipline to inter-disciplinary solutions to problems.

This graduate capability is supported by:

Learning outcomes

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Practical Reports
Introduction and Methods
Post Lecture Study questions
Mid-Semester Exam
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report
Final Examination

Critical, Analytical and Integrative Thinking

We want our graduates to be capable of reasoning, questioning and analysing, and to integrate and synthesise learning and knowledge from a range of sources and environments; to be able to critique constraints, assumptions and limitations; to be able to think independently and systemically in relation to scholarly activity, in the workplace, and in the world. We want them to have a level of scientific and information technology literacy.

This graduate capability is supported by:

Learning outcomes

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Define the major biological systems and control points involved in a range of fundamental cell processes;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Practical Reports
Introduction and Methods
Post Lecture Study questions
Mid-Semester Exam
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report
Final Examination

Problem Solving and Research Capability

Our graduates should be capable of researching; of analysing, and interpreting and assessing data and information in various forms; of drawing connections across fields of knowledge; and they should be able to relate their knowledge to complex situations at work or in the world, in order to diagnose and solve problems. We want them to have the confidence to take the initiative in doing so, within an awareness of their own limitations.

This graduate capability is supported by:

Learning outcomes

Students will have an understanding of how Biochemistry is used to determine cellular functions and how the cell uses Chemistry to achieve biological functions.
Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Be able to design experiments to characterise, quantitate and measure a range of fundamental cell processes;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Practical Reports
Introduction and Methods
Post Lecture Study questions
Mid-Semester Exam
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report
Final Examination

Effective Communication

We want to develop in our students the ability to communicate and convey their views in forms effective with different audiences. We want our graduates to take with them the capability to read, listen, question, gather and evaluate information resources in a variety of formats, assess, write clearly, speak effectively, and to use visual communication and communication technologies as appropriate.

This graduate capability is supported by:

Learning outcomes

Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Human Cell Atlas Assignment
Hot Topics Seminar
Final Report

Engaged and Ethical Local and Global citizens

As local citizens our graduates will be aware of indigenous perspectives and of the nation's historical context. They will be engaged with the challenges of contemporary society and with knowledge and ideas. We want our graduates to have respect for diversity, to be open-minded, sensitive to others and inclusive, and to be open to other cultures and perspectives: they should have a level of cultural literacy. Our graduates should be aware of disadvantage and social justice, and be willing to participate to help create a wiser and better society.

This graduate capability is supported by:

Learning outcomes

Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;
Contribute to the generation of new data and where appropriate entries in scientific databases.

Assessment tasks

Practical Reports
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report

Socially and Environmentally Active and Responsible

We want our graduates to be aware of and have respect for self and others; to be able to work with others as a leader and a team player; to have a sense of connectedness with others and country; and to have a sense of mutual obligation. Our graduates should be informed and active participants in moving society towards sustainability.

This graduate capability is supported by:

Learning outcomes

Possess an understanding of the application of various cell based experimental and routine methodologies fundamental to an understanding and measuring of normal cell biological processes and how disturbances in these can be involved in disease;
Be able to successfully communicate and critically analyse advanced molecular cell biological and biochemical concepts. Be able to communicate the research supporting these concepts both in both verbal and written form;

Assessment tasks

Practical Reports
Human Cell Atlas Assignment
Hot Topics Seminar
Final Report

Changes from Previous Offering

This unit has been upgraded substantially since the last offering. The most salient features of the updates are the integration of state of the art technologies and methodologies in cell biology techniques, and a focus on critical thinking aspects. Besides this, students are expected to participate in contributing knowledge to the scientific community inform of an eventual peer reviewed journal article.

Changes since First Published

Date	Description
09/07/2015	Co-badging and typographical corrections made. Rephrased some of the assessment tasks for clarity.