Students

CBMS333 – Functional Proteomics

2016 – S2 Day

General Information

Download as PDF
Unit convenor and teaching staff Unit convenor and teaching staff Unit Convenor
Paul Haynes
Contact via paul.haynes@mq.edu.au
Credit points Credit points
3
Prerequisites Prerequisites
39cp including (CBMS223 or CBMS224)
Corequisites Corequisites
Co-badged status Co-badged status
The 3 credit point unit CBMS333 shares the same lectures and tutorials as CBMS833. However, CBMS333 students are not required to submit the literature review essay, submit a laboratory practical report in a different format, are subject to different assessment marking schema, sit a different exam paper, and can expect distinct learning outcomes. From 2013 onwards, CBMS333 will also be co-taught with CBMS733 which is a postgraduate unit for students in the Master of Research degree program. The 3 credit point unit CBMS333 outlines chemical principles underlying the most recent developments in protein science and proteomics. The unit extends previous work undertaken in CBMS332, which included an understanding of the emerging new disciplines of proteomics, structural biology and bioinformatics. There is no formal prerequisite to complete CBMS332, but it is desirable. CBMS333 focuses on the proteomic methods used in the biotechnology and pharmaceutical industries to isolate, characterize, analyse and purify proteins using advanced proteomic technologies. The practical includes 1D and 2D protein gel separation, in-gel digestion of separated proteins, mass spectrometric analysis, database searching for protein identification, and shotgun proteomic quantitation. The learning outcomes for CBMS333 are focused on gaining discipline specific knowledge, understanding of the processes and technologies involved and how to apply them to answer biological questions, and hands-on practical experience in proteomics. CBMS333 is offered internally in second semester only. There are two hours of lecture time and two hours of tutorial time per week, plus a five full day practical component taught during semester break.
Unit description Unit description
Functional proteomics is the study of protein expression in living systems, considered in a functional context. This allows us to better understand how protein networks become dysfunctional, which in turn enables the manipulation of protein functions and cellular phenotypes through the use of drug treatment, or genetic or environmental intervention. This unit covers the principles and applications of functional proteomic techniques, and assumes basic knowledge of protein electrophoresis and mass spectrometry. Topics include: a detailed study of advanced techniques, instrumentation and protein identification software in mass spectrometry; two-dimensional differential gel electrophoresis; label-free and isotope-labelling quantitation in proteomics; application of different types of peptide- and protein-based shotgun proteomics approaches; characterisation of protein post-translational modifications including phosphorylation, glycosylation and others; and application of proteomics in the pharmaceutical industry. Students must attend a compulsory one week laboratory session during the semester break.

Important Academic Dates

Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates

Learning Outcomes

On successful completion of this unit, you will be able to:

  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment Tasks

Name Weighting Due
Oral Tutorial Presentation 25% From week 2 onwards
Continuing assessment 5% weekly
Mid-semester test 5% week 8
Practical Report 25% Friday October 16th
Final Exam 40% examination period

Oral Tutorial Presentation

Due: From week 2 onwards
Weighting: 25%

Oral Tutorial Presentation                                            25%

  • Choose one publication from the Tutorial Papers List (on a first-come first-served basis), which is found on a wiki on the iLearn site.
  • The papers are to be presented on the date indicated, because they are sorted by subject material. There is a small number of general interest papers at the end of the list which can be presented on any date you wish to choose.
  • A maximum of four presentations will be scheduled for each week. If you put your name down as the fifth person, you will miss out on presenting, so you will have wasted your time preparing a presentation.
  • Present your critique of the topic as a short Powerpoint seminar (generally 10 min talking with 5 mins questions but we may adjust that depending on class numbers)
  • Participation in all other group’s topics contributes to your final mark
  • Perform your own peer-review of your chosen paper - tell us whether you think this paper should have been published and why.
  • The research tutorial presentation will also be accepted as a video presentation uploaded in advance to Youtube. It must include figures, graphics, text (and some footage of the presenter). You can either record straight to video camera, or use software such as iMovie or Windows Movie Maker.

On successful completion you will be able to:
  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).

Continuing assessment

Due: weekly
Weighting: 5%

Continuing assessment: Weekly Speaker Questions      5%

You will be given 5 minutes at the end of each lecture in which you are required to write down and submit a question concerning the lecture for the the day. This must demonstrate some understanding of the topic that has been presented.


On successful completion you will be able to:
  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions

Mid-semester test

Due: week 8
Weighting: 5%

Mid-semester test                                                                        5%

This will typically be a multiple choice quiz, or other format, aimed at helping students assess their area of strength and weakness prior to the final exam. 


On successful completion you will be able to:
  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions

Practical Report

Due: Friday October 16th
Weighting: 25%

Practical Report (Due Friday October 14th)                                     25%

Non-submission will mean a Fail grade is recorded in CBMS333. You must complete a standard laboratory practical report which explains what you did during your experiments and what results you found. 


On successful completion you will be able to:
  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Gain hands-on practical experience in a range of proteomics techniques

Final Exam

Due: examination period
Weighting: 40%

Final Exam (2 hrs, date and time to be advised), 40%

2 hr exam covering all practical and theoretical components of CBMS333.

Questions are a mix of long and short answer questions.

 


On successful completion you will be able to:
  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions

Delivery and Resources

CBMS333 Functional Proteomics

 Other important items

  

-  We do not work from a textbook but we do have one book that is recommended reading and is available in the University bookstore: Proteomics for Biological Discovery, by Tim Veenstra and John R. Yates, published by Wiley Press.

 

Additional reading material is also included at the end of most lectures. It is your job to look it up.

 

- Technologies used and required. Lecture notes will be made available on the unit website in iLearn. Notes will be made available a few days in advance of the lecture whenever possible, and it is your responsibility to print them out.

 

- Technologies used and required. All of the important information during semester will be communicated to you via the unit website on iLearn. It is your responsibility to check it regularly for announcements and other information.

 

- The practical class is 5 days long and runs during semester break, so make plans now to be available for a week long practical class during that time.

 

- Technologies used and required. Students will need to have access to a computer and printer, and be able to use Word, Excel, Powerpoint, and a reference manager program such as EndNote.

 

- This unit is designed to build upon CBMS332 Protein Discovery and Analysis. That unit is not a prerequisite for entry into CBMS333 but passing CBMS832 is strongly recommended.

 

- What is changed? The unit is updated every year with revised lecture content and numerous new tutorial research papers. This reflects the rapidly changing state of the field.

 

- What is changed? from 2013 onwards the unit will also be offered at 700 level to Masters of Research students.

- What is changed? from 2014 onwards, the research tutorial presentation will now be accepted as a video presentation uploaded in advance to YouTube. It must include figures, graphics, text (and some footage of the presenter). You can either record straight to video camera, or use software such as iMovie or Windows Movie Maker.  

Unit Schedule

LECTURE, TUTORIAL and PRACTICAL TIMETABLE

 

Lectures: Wednesdays 12:00 pm - 2:00 pm August 3rd - November 9th, Room E7B100

Tutorials: Fridays 11:00 am - 1:00 pm, August 12th - November 11th, Room C5A 226

 

NOTE: the first scientific content lecture will be held in the first tutorial timeslot, Friday August 5th 11 – 1pm in E6A 133.

 

Practicals: Are held in a one-week block during semester break. You must be available for all of September 26th- 30th. Practical classes run all day, approximately 9am – 5 pm. This is the equivalent of 3+ hours per week for the whole semester, we just do it all at once. Attendance is compulsory - if you are not able to attend the practical class all week, for any reason, do not enrol in this unit.

The practical course includes differential display 2D gel electrophoresis, in-gel protein digestion, peptide spectrometry (MALDI-TOF/TOF and nanoESI-Linear ion trap), protein identification using Mascot and XTandem, shotgun proteomic analysis using SDS-PAGE protein fractionation, and label-free protein quantitation using normalized spectral abundance factors.

Up to date timetable information is found at timetables.mq.edu.au

All unit information is distributed using the unit website on ilearn, accessed via ilearn.mq.edu.au

 

 

 

Lectures Wednesdays 12pm-2pm, starting August 3rd, E7B100

 

Week

Date

Lecture Title

1

WEDNESDAY August 3rd

E7B100

Subject Outline and Assessment  Process, Scientific Writing, Introduction

1

FRIDAY

August 5TH

C5A226

Mass Spectrometry Fundamentals (in tutorial timeslot)

2

August 10th

Protein Identification from MS data

3

August 17th

2D gel Sample Preparation and troubleshooting

4

August 24th

2D-DIGE and experimental design

5

August 31st

Differential display and  shotgun proteomics

6

Sept 7th

Quantitative proteomics (I) label-free

7

Sept 14th

Quantitative proteomics (II) isotope labels 

Practical: 5 Days, 26th-30th September (during semester break)

8

October 5th

Spare timeslot – no lecture

9

October 12th

Multiple reaction monitoring and proteomics validation

10

October 19th

Protein-Protein Interactions

11

October 26th

Post-translational modifications (I)

Glycoproteomics

 

(continued)

 

Practical report due 9am Friday October 14th

12

November  2rd

Post-translational modifications (II) Phosphoproteomics

13

November  9th

Revision

 

All written work must be submitted through iLearn Turnitin. In addition, hardcopies of assignments and practical reports are to be handed in at the Science Centre in E7B, and are due in by 9am on the due date.

 

 

CBMS333 Functional Proteomics  

 

TUTORIAL TIMETABLE

Tutorials: Fridays 11-1pm from August 12th   

Room C5A 226

 

Week    Date                                                          

2              August 12th (note: August 5th is used for the first lecture)

3              August 19th

4               August 26th    

5               September 2nd   

6               September 9th                           

7               September 16th                       

 

                 Semester Break - September 17th to October 3rd

     

8              October 7th                     

9              October 14th

10            October 21st

11            October 28th

12            November 4th 

13            November 11th  (Only if required)

 

Learning and Teaching Activities

Lectures

Lecture material delivered in 2 hour blocks weekly.

Weekly follow-up

The first 15 minutes from each lecture are spent following up on questions raised from the previous weeks continuing assessment submissions.

Tutorials

Students present a 10-15 minute presentation on a scientific paper they have selected from a list.

Practical Class

Students spend five whole days in practical class during one week of semester break.

Policies and Procedures

Macquarie University policies and procedures are accessible from Policy Central. Students should be aware of the following policies in particular with regard to Learning and Teaching:

Academic Honesty Policy http://mq.edu.au/policy/docs/academic_honesty/policy.html

New Assessment Policy in effect from Session 2 2016 http://mq.edu.au/policy/docs/assessment/policy_2016.html. For more information visit http://students.mq.edu.au/events/2016/07/19/new_assessment_policy_in_place_from_session_2/

Assessment Policy prior to Session 2 2016 http://mq.edu.au/policy/docs/assessment/policy.html

Grading Policy prior to Session 2 2016 http://mq.edu.au/policy/docs/grading/policy.html

Grade Appeal Policy http://mq.edu.au/policy/docs/gradeappeal/policy.html

Complaint Management Procedure for Students and Members of the Public http://www.mq.edu.au/policy/docs/complaint_management/procedure.html​

Disruption to Studies Policy http://www.mq.edu.au/policy/docs/disruption_studies/policy.html The Disruption to Studies Policy is effective from March 3 2014 and replaces the Special Consideration Policy.

In addition, a number of other policies can be found in the Learning and Teaching Category of Policy Central.

Student Code of Conduct

Macquarie University students have a responsibility to be familiar with the Student Code of Conduct: https://students.mq.edu.au/support/student_conduct/

Results

Results shown in iLearn, or released directly by your Unit Convenor, are not confirmed as they are subject to final approval by the University. Once approved, final results will be sent to your student email address and will be made available in eStudent. For more information visit ask.mq.edu.au.

Guidelines for preparation of written work

ALL WRITTEN WORK MUST BE ORIGINAL. Students are sometimes tempted to use material which is not their own without due acknowledgment.  This constitutes cheating, the penalty for which is failure of the course.  It is considered equivalent to cheating in an examination.  Direct copying and/or submitting material from your own work done in previous years is also considered cheating.

WHAT CONSTITUTES CHEATING?

Collusion

Collusion is the secret and fraudulent production of identical or superficially altered work submitted for assessment by two or more students.  It is easily detected by the examiner from the similarity in styles.  This constitutes cheating and will be dealt with accordingly.

Plagiarism

Plagiarism is the verbatim use of someone else's work, as if it were your own.  This also constitutes cheating and will be dealt with accordingly.  The "someone else" concerned may be an author, critic, lecturer, or even a fellow student.  Plagiarism includes copying of material from practical books obtained from other students in the same or previous years.  It also includes the direct copying of material from texts, references and other sources.  It is important to realize that it does not make it acceptable to reproduce a sentence or paragraph from a published source when you add the name or number of the reference at the end.

If you need to quote another piece of work, do it correctly.  You must provide quotation marks around the quotation and this must be referenced.  In other words, the only proper way to indicate that the words are not yours is to show clearly that they are a quotation. 

It is often desirable and may even be necessary to use other people's ideas but you must not pretend that they are your own.  In such cases, your text should include a reference to the source of the idea. You may need to use a figure or table from another source.  If so, the legend must indicate the source, with the appropriate reference. The list of referees should include acknowledgment of ideas, data and direct quotations from all sources.

More information regarding the University policy on academic honesty can also be found at http://www.mq.edu.au/policy/docs/academic_honesty/policy.html.

Collaboration

Students are often required to work cooperatively in groups when performing experiments.  This may be necessitated by limitations on the amount of equipment or experimental material available, or simply by the fact that more than one pair of hands is required to do the experiments.  Such collaboration is common and is an essential part of scientific endeavour.  However, collaboration must always be acknowledged.

When you perform experimental work as part of a group, you must always acknowledge the collaboration by writing the names of the other members of the group at the start of your practical report.

Collaboration in performing an experiment does not extend to writing a report on the experiment where that report is assessed for marks.  Students must prepare their own report individually.

 

Guidelines for preparation of written work

WHAT IS REQUIRED?

References

Essay and practical reports need scientific references to support facts and ideas that you are referring to. These should be primarily journal articles from recent scientific literature. You should only rarely need to cite textbooks; everything in a textbook was most likely published elsewhere in the literature long before the book was published. You should not refer to websites such as Expasy or NCBI for general information; gel images in Expasy for example, have also been published elsewhere in the scientific literature. You should NEVER refer to Wikipedia or to tutorial information posted on the web at another university. The reason for these rules is that textbooks, websites and Wikipedia are not primary sources, they are compilations of previously published material. More importantly, they are not peer-reviewed (including textbooks) so the authors can say whatever they like on a topic whether it is right, or not.

Learn to use Endnote or a similar program to manage and cite your references. This will make your written work look more polished and will avoid simple mistakes which cost you marks. Endnote is available as a free download from the MQ library, along with simple online tutorials in how to use it. Format references in your work according to the guidelines of any of the following journals: Analytical Biochemistry, Journal of Biological Chemistry, Journal of Proteome Research, Molecular and Cellular Proteomics, or Proteomics. The most common error students make with references is that the references in a list are inconsistent in style – they all need to be exactly the same format.

What is an essay?

An essay is a written discourse on a topic. It has a defined introduction, middle and conclusion, and contains logical arguments that follow a clear sequence. An essay does not contain dot point lists, and does not need to contain subheadings. It can contain table and figures to illustrate a point. If these are copied from a reference it needs to state that explicitly in the Figure legend or table footnote. Tables and figures should be numbered sequentially in order of their appearance in the text, and can either be inserted into the text or collated at the end. Every figure needs an explanatory legend, most tables need a footnote or two to explain the meaning of column headings. An essay has relevant references formatted as described earlier and collected at the end of the text.

What is a practical report?

A practical report has a title, aim, introduction, materials and methods, results, discussion, and references. It is divided into sections under these headings. It usually contains figures, and may contain tables as well. If these are copied from a reference it needs to state that explicitly in the Figure legend or table footnote. Tables and figures should be numbered sequentially in order of their appearance in the text, and can either be inserted into the text or collated at the end. Every figure needs an explanatory legend, most tables need a footnote or two to explain the meaning of column headings.

The aim of the experiment should be clearly stated. The methods should not just be copied directly from the course manual or notes. The results should describe what you observed, irrespective of whether you think it “worked” or not. Discussion should compare your observed results with literature or other experiments in class, especially if you have positive controls to work with.  A practical report has relevant references formatted as described earlier and collected at the end of the text.

HINTS ON HOW TO USE SCIENTIFIC JOURNALS

During CBMS333 we will use current research (as distinct from partially digested textbook examples) to illustrate principles.  The most up-to-date information is published in scientific journals. 

CBMS333 students need to read journal articles to supplement the information given in lectures and practical notes.  Your own reports should be modeled on the style of scientific papers (so take careful note of their presentation).  It is important that you become efficient at using the large amount of information available.  A huge number of journals and papers are available.  The following paragraphs give you some guidance in doing this efficiently.

If everyone read scientific papers with care, effort and attention to detail, we would have to read a lot less.  Develop an economical reading style and avoid too much rereading. In addition:-

1.       Do not read through the paper from start to finish. A journal article is NOT a novel (though the results and ideas may be!). The various sections are there for good reasons.

2.       Read and think about the Title. "Is the paper really about the subject matter I thought it was?  Do I need to read it at all?"

3.       Read the Abstract (or Summary) to confirm the suspicions formed in 2.  This section should give you an idea of the main results and why they are important.  Ask yourself:  "Do I need to read further?  Is this paper appropriate?"  This is especially important if you have uncovered the reference in another paper or from Science Citation Index or Current Contents. Titles often suggest that the paper is more relevant than it really is.

4.       If you continue, now read the Results. Examine the figures and tables.  They should be self-explanatory. (This is something that you must bear in mind when you prepare your own report. Good captions and labels are vital).  What do the results mean? How convincing are they? Now look at the Discussion. Do your interpretations of the data and conclusions agree with those of the author(s)?

5.       How do these experiments fit in with the general research field and with current theories? In other words, why was the research conducted? This should be established in the Introduction.

Despite the efforts of editors and reviewers there are bad papers as well as good papers in the published literature. Some are badly presented, but contain basically good work. You have to plough through those to extract the gems of wisdom. Others look great on the surface but say nothing of importance. You should train yourself to recognize these quickly without wasting time on them. To help you here, look carefully at the following:-

 (a)    What are the hypotheses (or questions) posed in the paper?  (Be careful that you are not simply forming your own idea of what the paper is testing.)

(b)     What approach is used to collect the data (see Methods section).

(c)     Do the data, and the manner of collection allow a DIRECT TEST of the hypothesis?  If not, what sort of experiment would?

(d)     Are there interpretations of the Results which you would make but which have been ignored by the author(s)?

You should try to bear these points in mind when you are reading any papers, but it will be especially important when reading the key papers for your reports, major essay and tutorial presentation.  We expect that you will show evidence of having evaluated the strengths of published work.

TIMELY SUBMISSION

ALL CBMS333 assessment deadlines must be met

  • Late submissions will be penalised with 10% loss of the maximum mark for each day past the deadline. 
  •  If there is any medical reason why you cannot submit work on time or if you cannot give your tutorial topic for any reason, you should contact the course convenor as early as possible, before the due date.
  •  Copies of medical certificates MUST be forwarded to the course convenor as soon as possible. Failure to do so will incur a zero mark for non-submission.

EXAMINATION POLICY

•          As with all subjects in the Department of Chemistry and Biomolecular Sciences, your final mark has a large component of continual assessment. 

•          Since your final mark is the sum of all components of this subject, you should approach this subject in a consistent and diligent manner throughout the session; leaving your best effort to the final examination period would be most unwise. 

•          Remember, marks are deducted from the continuous assessment component if you are absent without cause or if your submissions are late.

•          Despite the presence of a significant continuous assessment component in CBMS333, you will be required to achieve a satisfactory grade in the final exam in order to pass CBMS333. In the event you fail this unit, you can NOT request a supplementary examination or re-examination simply because you failed.

•          The final examination is typically 2 hours long, but may be longer if required.

 

CBMS333 LABORATORY SAFETY POLICY

1.         Laboratory coats and sensible fully enclosed footwear (no thongs or open-toed sandals) must be worn in the research lab at all times. Lab coats should be removed prior to entering common areas (eg: hallways, tea rooms).

2.         Smoking, eating and drinking are not permitted at any time in any lab.

3.         You are responsible for the smooth and efficient operation of your work area. Keep your assigned work areas as tidy as possible (e.g., clean and store any used items when no longer required; return any communal reagents to their assigned place in the laboratory). Do not leave a mess for someone else (eg: co-workers or Departmental technical staff) to clean up.

4.         You might be handling bio-hazardous or radioactive materials during your practicals.  Mouth pipetting is NOT allowed at any time.  The Chemistry and Biomolecular Sciences Department has a complete Safety Manual which you may refer to at any time prior to undertaking a hazardous task. In order to provide a safe working environment, please take this request most seriously.

5.         All instructions for the handling of:

(a)               biohazardous and radioactive material;

(b)               micro-organisms;

(c)               recombinant materials; and

(d)               research equipment

must be carefully adhered to.

6.   Some practical exercises may involve the examination of human fluids, human cells or human cell lines.  There should be no sharing of this material or any of the instruments used to collect them. 

 

DISRUPTION TO STUDIES AND SUPPLEMENTARY EXAMINATIONS POLICY

The rules regarding special consideration and supplementary examinations are set out in full in the University Undergraduate Calendar. The following is a summary.

1.     What is a request for Disruption to studies?

       A request for the Department to take into account, when assessing your performance in any assignment or examination, circumstances beyond your control: typically medical problems or other compassionate circumstances. Forms regarding the Disruption to studies process are available at:

www.reg.mq.edu.au/Forms/APSCons.pdf

2.   What are acceptable reasons for Disruption to studies?

(i)     valid medical, compassionate and serious unforeseen personal events that prevent a student from meeting scheduled deadlines,

(ii)    validated conflicts between scheduled assessments and sporting, cultural or other activities at a national or international level: these must be raised well in advance with the Department.

3.     How do you apply?

(i)     Lodge a written application, together with supporting documentation, with the Student Enquiries Office in Admin. Or do it online at ask.mq.edu.au.

(ii)    Do this no later than 7 days following the serious illness or other situation. Admin. will pass it on to the Department.

(iii)   It is your responsibility to check the outcome with the Department, not later than two weeks after lodging the application.

4.     What is “supporting documentation”?

(i)     A medical certificate, which states the date or dates of any relevant consultations or attendances, the nature of the problem and the treatment; and a specific statement that the student was unfit to complete the required assessment or examination on the date specified. Medical certificates which do not have all this information will not be accepted.

(ii)    A letter from the University Counselling Service, or a professional counsellor, which sets out the general nature of the problem affecting the student, and the opinion of the counsellor that the student was unfit to complete the required assessment

(iii)   A statutory declaration, setting out the facts upon which Disruption to studies is requested, and attaching any supporting documents.

Note:  A letter from an employer, friend, religious advisor etc. is not sufficient.

5.     Supplementary exams?

(i)     These are granted only under special conditions: (a) if the student did not sit the standard examination for an acceptable reason; or (b) if the student, after reporting the illness to the Supervisor-in-Charge, left the examination room because of verified illness.

(ii)    Early exam/assessment will not be permitted on the grounds of lengthening the period available for holidays or for departure overseas before the end of the exam period.

6.     Timing of Supplementary Assessment

(i)     Supplementary assessment is to be completed at a time convenient to the Department. It is the responsibility of the applicant to comply with the requirements of the Department.

(ii)    It is your responsibility (a) to be available to sit for the exam at any time during the vacation period immediately following the application; AND (b) to leave a contact address and telephone number with the Department.

7.     Forms of Supplementary Assessment

        Supplementary theory and practical exams may require different and additional assessment tasks to the normal examination. Supplementary examination may be in individual, oral format.

Student Support

Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/

Learning Skills

Learning Skills (mq.edu.au/learningskills) provides academic writing resources and study strategies to improve your marks and take control of your study.

Student Services and Support

Students with a disability are encouraged to contact the Disability Service who can provide appropriate help with any issues that arise during their studies.

Student Enquiries

For all student enquiries, visit Student Connect at ask.mq.edu.au

IT Help

For help with University computer systems and technology, visit http://www.mq.edu.au/about_us/offices_and_units/information_technology/help/

When using the University's IT, you must adhere to the Acceptable Use of IT Resources Policy. The policy applies to all who connect to the MQ network including students.

Graduate Capabilities

Creative and Innovative

Our graduates will also be capable of creative thinking and of creating knowledge. They will be imaginative and open to experience and capable of innovation at work and in the community. We want them to be engaged in applying their critical, creative thinking.

This graduate capability is supported by:

Learning outcomes

  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Oral Tutorial Presentation
  • Continuing assessment
  • Mid-semester test
  • Practical Report

Capable of Professional and Personal Judgement and Initiative

We want our graduates to have emotional intelligence and sound interpersonal skills and to demonstrate discernment and common sense in their professional and personal judgement. They will exercise initiative as needed. They will be capable of risk assessment, and be able to handle ambiguity and complexity, enabling them to be adaptable in diverse and changing environments.

This graduate capability is supported by:

Learning outcomes

  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Oral Tutorial Presentation
  • Continuing assessment
  • Practical Report

Commitment to Continuous Learning

Our graduates will have enquiring minds and a literate curiosity which will lead them to pursue knowledge for its own sake. They will continue to pursue learning in their careers and as they participate in the world. They will be capable of reflecting on their experiences and relationships with others and the environment, learning from them, and growing - personally, professionally and socially.

This graduate capability is supported by:

Learning outcomes

  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Continuing assessment
  • Mid-semester test
  • Practical Report
  • Final Exam

Discipline Specific Knowledge and Skills

Our graduates will take with them the intellectual development, depth and breadth of knowledge, scholarly understanding, and specific subject content in their chosen fields to make them competent and confident in their subject or profession. They will be able to demonstrate, where relevant, professional technical competence and meet professional standards. They will be able to articulate the structure of knowledge of their discipline, be able to adapt discipline-specific knowledge to novel situations, and be able to contribute from their discipline to inter-disciplinary solutions to problems.

This graduate capability is supported by:

Learning outcomes

  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Oral Tutorial Presentation
  • Continuing assessment
  • Mid-semester test
  • Practical Report
  • Final Exam

Critical, Analytical and Integrative Thinking

We want our graduates to be capable of reasoning, questioning and analysing, and to integrate and synthesise learning and knowledge from a range of sources and environments; to be able to critique constraints, assumptions and limitations; to be able to think independently and systemically in relation to scholarly activity, in the workplace, and in the world. We want them to have a level of scientific and information technology literacy.

This graduate capability is supported by:

Learning outcomes

  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Oral Tutorial Presentation
  • Continuing assessment
  • Mid-semester test
  • Practical Report
  • Final Exam

Problem Solving and Research Capability

Our graduates should be capable of researching; of analysing, and interpreting and assessing data and information in various forms; of drawing connections across fields of knowledge; and they should be able to relate their knowledge to complex situations at work or in the world, in order to diagnose and solve problems. We want them to have the confidence to take the initiative in doing so, within an awareness of their own limitations.

This graduate capability is supported by:

Learning outcomes

  • Understand technologies used in proteomics
  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Exhibit a sound knowledge of how to apply proteomics technologies to answer biological questions
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Continuing assessment
  • Mid-semester test
  • Practical Report
  • Final Exam

Effective Communication

We want to develop in our students the ability to communicate and convey their views in forms effective with different audiences. We want our graduates to take with them the capability to read, listen, question, gather and evaluate information resources in a variety of formats, assess, write clearly, speak effectively, and to use visual communication and communication technologies as appropriate.

This graduate capability is supported by:

Learning outcomes

  • Comprehend the chemical, biochemical and biophysical processes involved in proteomics
  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Mid-semester test
  • Practical Report
  • Final Exam

Engaged and Ethical Local and Global citizens

As local citizens our graduates will be aware of indigenous perspectives and of the nation's historical context. They will be engaged with the challenges of contemporary society and with knowledge and ideas. We want our graduates to have respect for diversity, to be open-minded, sensitive to others and inclusive, and to be open to other cultures and perspectives: they should have a level of cultural literacy. Our graduates should be aware of disadvantage and social justice, and be willing to participate to help create a wiser and better society.

This graduate capability is supported by:

Learning outcome

  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Oral Tutorial Presentation
  • Practical Report

Socially and Environmentally Active and Responsible

We want our graduates to be aware of and have respect for self and others; to be able to work with others as a leader and a team player; to have a sense of connectedness with others and country; and to have a sense of mutual obligation. Our graduates should be informed and active participants in moving society towards sustainability.

This graduate capability is supported by:

Learning outcomes

  • Extract information from a recent publication in a contemporary area of proteomics, and communicate to their peers a summary of the results and significance of the publication (tutorial topic).
  • Gain hands-on practical experience in a range of proteomics techniques

Assessment tasks

  • Oral Tutorial Presentation
  • Mid-semester test
  • Practical Report