Unit convenor and teaching staff |
Unit convenor and teaching staff
Convenor and Lecturer
Andrew Try
Contact via 9850 8291
F7B 228
Arrange via email
Lecturer
Peter Karuso
Contact via 9850 8290
F7B 232
Arrange via email
Lecturer
Fei Liu
Contact via 9850 8312
F7B 330
Arrange via email
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Credit points |
Credit points
3
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Prerequisites |
Prerequisites
CBMS204 and (3cp from CBMS200-CBMS203 or CBMS205-CBMS234)
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Corequisites |
Corequisites
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Co-badged status |
Co-badged status
CBMS804
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Unit description |
Unit description
Biological systems carry out a huge range of complex organic reactions to achieve growth, to reproduce and to compete. This unit, together with CBMS303, examines advanced topics in organic chemistry, relevant to biology and biological systems. This unit has an underlying theme of the structure and reactivity of DNA. Specific topics include: metal-mediated coupling (bond-forming) reactions; aromaticity; heterocyclic chemistry; nucleotides, DNA and RNA; and pericyclic reactions. These topics build upon the foundation of CBMS204, using the same text book supplemented by notes given out in lectures and inexpensive Oxford Chemistry Primers on specialised topics. This unit requires good skills in organic chemistry; a background in other aspects of chemistry and/or biochemistry will be advantageous. The laboratory sessions are aimed at developing skills in organic chemistry, using reactions studied in lectures to reinforce principles and exemplify typical reactions.
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Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates
On successful completion of this unit, you will be able to:
Name | Weighting | Due |
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Quiz and Workshop performance | 10% | Throughout semester |
Practical Performance | 25% | See description |
Mid-semester Test | 10% | To be advised |
Final Examination | 55% | To be advised |
Due: Throughout semester
Weighting: 10%
Answering and explaining questions
Due: See description
Weighting: 25%
Pre-work (mechanisms, flow chart and safety data), laboratory report, including procedures, reults, analysis, conclusions and answering post-lab questions
Due date: Reports due 1 week after conclusion of the relevant lab
Due: To be advised
Weighting: 10%
Will cover the first 6 weeks of the unit.
Due: To be advised
Weighting: 55%
It is designed to address specific understanding of all the topics presented within the course and to show that the knowledge obtained can be applied to new problems
Classes
CBMS304 is a traditional Chemistry subject that is organised around lectures and laboratories (5 different experiments). Lectures will be on Fridays (11-1 E7A 133), with labs on Friday (2-6pm E7B 349, Third Year Laboratory), except for weeks 5, 9 and 13 (when there will be workshops instead of the Wednesday Labs (room to be advised, 2-6 pm and attendance at these sessions is compulsory). These 3 workshops are problem solving sessions associated with the three sections of the course (more details later).
The timetable may be subject to change so please check on the University web site.
Spot tests will be run in the lecture classes. The lab notes, which include safety information and tips on writing the reports are available from the CBMS304 web page on iLearn.
Labs will open at 2 pm and you must wear closed shoes, a lab coat and safety glasses. More detailed instructions are given in the lab notes. Laboratory work must cease at 5:45 pm.
All the equipment and glassware used in the laboratory classes is very expensive. Please handle everything with care. Please also clean and put away all the glassware that you used. In addition, before you leave ensure that you wipe down you work area, turn off all gas, water and electricity you turned on and place all residues in the appropriate waste containers.
The laboratory will close at 6:00 pm. All students are expected to be out at this time.
Required and Recommended texts and/or materials
Required texts (all placed in Reserve in the Library)
Supplementary texts (all restricted to 7 day loan in the library)
Garrett, R. and Grisham, C.M. Biochemistry, Fort Worth, Saunders College Pub., 1999. QD415.G29/1999
Smith, W.B. Introduction to Theoretical Organic Chemistry and Molecular Modeling, New York: VCH Publishers, c1996. QD476.S567/1996
Gilchrist, T.L. Heterocyclic Chemistry, Longman Scientific & Technical. QD400.G55/1997
Gilchrist, T.L. Organic Reactions and Orbital Symmetry, New York: Wiley, c1976. QD476.G54/1979
Joule J.A. and Mills K. Heterocyclic Chemistry, 4th edition, Oxford, Blackwell Science Ltd, 2000. QD400.J59/2000 (available in the Reserve section of the library)
Bellamy, Anthony J. An Introduction to Conservation of Orbital Symmetry. Longman, 1974. QD476.B363
Fleming, Ian. Frontier Orbitals and Organic Chemical Reactions, Wiley, London 1990, c1978.
QD461.F53/1978
Henderson, Richard, The Mechanisms of Reactions at Transition Metal Sites, Oxford University Press, 1993. QD172.T6 .H46/1993
Thomas, Susan. Organic Synthesis—The Roles of Boron and Silicon, Oxford; Oxford University Press, 1991 QD412.B1 .T56/1991
For those that are really keen
Entwistle, Norman. Orbital Symmetry Correlations in Organic Chemistry. London: Van Nostrand Reinhold, 1972. QD476.E5
Meijere, de Armin; Diederich, Francois. Metal-Catalyzed Cross-Coupling Reactions, Wiley-VCH, 2004. QD262.M48 2004 vol 1
Unit web page
The web page is accessed via the iLearn site. You are expected to access the web pages regularly, where you may find announcements, links to interesting internet facilities and sites of interest to the course, downloadable software, and lots of other interesting stuff.
Technology Used
You are expected to access the unit web site on a frequent basis and download pdf files.
Macquarie University policies and procedures are accessible from Policy Central. Students should be aware of the following policies in particular with regard to Learning and Teaching:
Academic Honesty Policy http://mq.edu.au/policy/docs/academic_honesty/policy.html
Assessment Policy http://mq.edu.au/policy/docs/assessment/policy.html
Grading Policy http://mq.edu.au/policy/docs/grading/policy.html
Grade Appeal Policy http://mq.edu.au/policy/docs/gradeappeal/policy.html
Grievance Management Policy http://mq.edu.au/policy/docs/grievance_management/policy.html
Disruption to Studies Policy http://www.mq.edu.au/policy/docs/disruption_studies/policy.html The Disruption to Studies Policy is effective from March 3 2014 and replaces the Special Consideration Policy.
In addition, a number of other policies can be found in the Learning and Teaching Category of Policy Central.
Macquarie University students have a responsibility to be familiar with the Student Code of Conduct: https://students.mq.edu.au/support/student_conduct/
Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/
Learning Skills (mq.edu.au/learningskills) provides academic writing resources and study strategies to improve your marks and take control of your study.
Students with a disability are encouraged to contact the Disability Service who can provide appropriate help with any issues that arise during their studies.
For all student enquiries, visit Student Connect at ask.mq.edu.au
For help with University computer systems and technology, visit http://informatics.mq.edu.au/help/.
When using the University's IT, you must adhere to the Acceptable Use Policy. The policy applies to all who connect to the MQ network including students.
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