- Lectures will be twice weekly: Tuesday (9 am) in W5C 320 and Wednesday (9 am) in W5C 220.
- The course syllabus is defined by the subject material presented in all lectures (including guest lectures) and practicals, much of which is beyond standard textbooks.
- From week 2, tutorials run for all students thrice a week: Tuesday (10 am) in W6B 382, Tuesday (12pm) in E7B 200 and Wednesday (5 pm) in E5A 120. These are structured as problem-solving workshops. You are required to attend for either of the three sessions.
A block chromatography workshop (workshop_1 to workshop_5) is scheduled in the first week of mid-semester break, i.e. from April 18 – 21 and April 24.
CBMS 832 students are required to attend ONLY Workshop 3 and 4 scheduled for Apr 20-21, (Thur-Fri).
- During session, practicals (named Practical_1 in the University timetable) are scheduled on several Wednesday afternoons (11am-3pm). You will attend for 4 afternoons, according to your allocated laboratory group (detailed in the table below).
- You will be allocated a lab group (Group 3 or Group 4) by the Unit convenor and communicated via the iLearn interface.
- Participation is compulsory on the allocated days of class. If you are sick, please consult with the Unit Convenor to ensure all laboratory and project work is completed. Outstanding reports will result in failure of this Unit.
- Please carefully check the location of each laboratory activity, as classes start promptly. Latecomers may be excluded from class.
- You are not permitted to change groups during semester.
Required and Recommended texts
- The textbook of which you are expected to purchase a personal copy is: “Physical Biochemistry: Principles and Applications”, David Sheehan, John Wiley (2nd ed, 2002). Online access of the text is available on the MQ Library website.
- Because of the multidisciplinary nature of this course, you will be expected to read more widely than this, however. The library has an excellent collection of up-to-date reference material to cover the course and laboratory subjects - explore it!!
- Strongly recommended reference texts available in the library (short-term loan only):
- “Proteins: Structure and Function”, D. Whitford, John Wiley, 2005
- “Protein Structure and Function”, Petsko & Ringe, New Science Press, 2009
- “Introduction to Protein Structure”, Branden & Tooze, Garland, 1999
- “Purifying proteins for proteomics : a laboratory manual” ed. R.J. Simpson. Cold Spring Harbor Laboratory Press, 2004
- Other general references that you may find useful are:
- R. Scopes, "Protein purification: principles and practice", New York, Springer-Verlag, 1994
- Garrett & Grisham, “Biochemistry” (esp. Chs 4 – 6), Harcourt Brace, 2013
- T. Creighton, “Proteins: Structures and Molecular Properties”, Freeman, 1993
The Unit will run as an online unit within iLearn (http://learn.mq.edu.au). Within this Unit, you will be introduced to Web-based tools, search engines and graphics software that are commonly used today in protein science. There are many excellent websites, apps and YouTube presentations to show how protein are made and constantly move around.
It is an expectation that you will become familiar with the following sites during the course:
- You will require access to the internet and have a computer available for accessing the iLearn site, web browsing, preparation of your reports and presentations (Word and PowerPoint software), molecular viewing and case study analysis. Printer access is required to generate hard copy of reports.
- Your project and laboratory reports will be electronically submitted via the online Turnitin program within the CBMS332/732/832 iLearn portal.
- Your practical reports will require you to carry out minor computational tasks, for which a calculator and access to basic statistical software will be required.
- We place a strong emphasis on correct referencing style in all your reports. Use of the program EndNote (http://libguides.mq.edu.au/EndNoteMac, http://libguides.mq.edu.au/EndNotePC ) is encouraged, but not essential.
- The capacity to download and install a simple molecular graphics program will assist you greatly in the Unit. Your model-building assessment task can be carried out with very simple materials; it is not an expectation that expensive art supplies need be purchased.