Students
BIOL376 – Advanced Human Physiology
2018 – S1 External
General Information
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| Unit convenor and teaching staff |
Unit convenor and teaching staff
Convenor
Julia Raftos
Contact via email
E8A 207
Class Scientific Officer
Prasanth Subramani
Contact via email
E8A 103
Tutor
Anu Jayaweera
Contact via email
Tutor
Jane AL Kouba
Contact via email
Tutor
Minakshi Das
Contact via email
Tutor
Charmaine Lo
Contact via email
Tutor
Susie Hewlett
Contact via email
Tutor
Rajib Majumder
Contact via email
Caitlin Kordis
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| Credit points |
Credit points
3
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| Prerequisites |
Prerequisites
(BIOL247 and BIOL257) or (admission to BHumanSc or BA-PsychBHumanSc or BPsych(Hons)BHumanSc or BSpHLScBHumanSc and 6cp at 200 level including BIOL247)
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| Corequisites |
Corequisites
HLTH306 or HLTH310 or HLTH316 or HLTH317 or BIOL345 or BIOL367 or CBMS306 or CBMS335 or CBMS337 or PSY354 or STAT395
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| Co-badged status |
Co-badged status
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| Unit description |
Unit description
This unit follows on from BIO257 and BIOL247. We will investigate the interaction of the renal and respiratory systems in the control of body pH. The next topic is the control of blood pressure leading to a discussion of hypertension and exercise. We continue with endocrinology discussing signal transduction and messenger pathways, and the role of hormones in the regulation of plasma potassium, calcium and glucose concentrations. A discussion of neuroendocrine systems and function of thyroid, sex, growth, mineralocorticoid and glucocorticoid hormones leads into a discussion of stress and the stress hormones. As obesity is currently a major threat to human health we will consider energy balance and the neurological basis for homeostatic and hedonic control of appetite before investigating other factors involved in weight control including genetics, foetal programming, protein leverage and the gut microbiota. The final two lectures will be on the neurobiology of the reward systems involved in hedonic eating and drug addiction. Practical classes make use of computer-assisted learning, as well as laboratory experiments. We will measure physiological parameters such as blood pressure during exercise, acid and base in the urine and stress hormones in the saliva. In these classes students will act both as investigators and experimental subjects.
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Important Academic Dates
Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates
Learning Outcomes
On successful completion of this unit, you will be able to:
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
- Identify the components of the neural and endocrine systems that maintain energy balance in the human body
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
General Assessment Information
Students are expected to attend all the practical classes and there will be questions on the material covered in the practical classes in the mid-semester test and the final examination.
If you receive special consideration for the final exam, a supplementary exam will be scheduled in the interval between the regular exam period and the start of the next session. By making a special consideration application for the final exam you are declaring yourself available for a resit during the supplementary examination period and will not be eligible for a second special consideration approval based on pre-existing commitments. Please ensure you are familiar with the policy prior to submitting an application. You can check the supplementary exam information page on FSE101 in iLearn (bit.ly/FSESupp) for dates, and approved applicants will receive an individual notification one week prior to the exam with the exact date and time of their supplementary examination.
A hurdle requirement is an activity for which a minimum level of performance or participation is a condition of passing a unit. In BIOL376 the final exam is the hurdle assessment and the university has stipulated that if you have made a serious attempt but failed to pass a hurdle requirement you will be given a second chance to attain a passing grade. The pass mark for the final exam is 45%. Students who have a mark of 35 to 44% will be able to sit the exam again. The exam papers for the first and second attempts will be the same in style (i.e. multiple choice and short answer questions) but the actual questions will be different.
If you are given a second opportunity to sit the final examination as a result of failing to meet the minimum mark required, you will be offered that chance during the same supplementary examination period and will be notified of the exact day and time after the publication of final results for the unit .
Assessment Tasks
| Name | Weighting | Hurdle | Due |
|---|---|---|---|
| Exercise assignment | 5% | No | internals 26/03/2018 |
| Acid /base balance assignment | 5% | No | 30/04/2018 |
| Mid semester test | 10% | No | Internals week 7 |
| Essay | 10% | No | 30/04/2018 |
| Seminar | 10% | No | Weeks 9 and 10 |
| Formal exam | 60% | Yes | End of semester exam period |
Exercise assignment
Due: internals 26/03/2018
Weighting: 5%
Students will answer the series a the questions that investigate the physiological significance of the results from the exercise practical. The exercise questions are in the practical manual and the assignment must be written in your own words and submitted through Turnitin.
Due date for internal students is 26/03/2018 and for external students 02/04/2018
On successful completion you will be able to:
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
- Identify the components of the neural and endocrine systems that maintain energy balance in the human body
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Critically evaluate information and form logical arguments supported by experimental evidence
Acid /base balance assignment
Due: 30/04/2018
Weighting: 5%
In this assignment, excretion rates of the control and treatment groups will be compared. To do this the time courses of the urine excretion rates, total acid excretion rates, urine pH, and the rates of bicarbonate excretion will be plotted. Students will answer a series of questions that are designed to probe the physiological mechanisms that produce the experimental results. The details of this assignment are in the practical manual
The assignment must be written in your own words and submitted through Turnitin.
The due date for both internal and external students is 30/4/2018.
On successful completion you will be able to:
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Critically evaluate information and form logical arguments supported by experimental evidence
Mid semester test
Due: Internals week 7
Weighting: 10%
This test will include 35 multiple choice questions to be completed in 60 minutes. All the material in lectures 1-10 and the material presented in the practical classes will be included in the test.
For internal students the test will be held in the normal practical class in week 7. External students will do their test during the second on-campus session on 18/04/2018 at 9 am.
On successful completion you will be able to:
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
Essay
Due: 30/04/2018
Weighting: 10%
The essay will be of 1,500 words and the topic will be chosen from the list on the iLearn site. The essay must be written in your own words. The main criterion for marking will be the physiological content but writing style will also be considered. The rubric used to mark the essay is on the iLearn site.
The source of all statements and diagrams obtained from the literature must be cited. The reference list only contains the articles that you have actually cited in the essay. Citations and the reference list should be in Harvard Style. For more information go to
www.bio.mq.edu.au/files/Harvard%20Referencing%20System%202012(5).pdf
The essay must be written in your own words and submitted through Turnitin.The due date for both internal and external students is 30/4/2018.
On successful completion you will be able to:
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Seminar
Due: Weeks 9 and 10
Weighting: 10%
The seminar topics will be the same as your essay topic. You will present your seminar as part of a team of three students. Each seminar is of 15 minutes duration with an extra 5 minutes of question time. There will be time during the practical sessions for you to decide on the distribution of tasks between team members. All three students must present part of the seminar and answer questions from the audience.
The main criterion for marking will be the quality of presentation although the physiological content will also be considered and the rubric used to mark the seminar is included on he ilearn site
External students will present their seminars during the second on-campus session on 19/04/2018 starting at 9 am.
On successful completion you will be able to:
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Formal exam
Due: End of semester exam period
Weighting: 60%
This is a hurdle assessment task (see assessment policy for more information on hurdle assessment tasks)
The exam is a three hour paper. One third of the marks will be for multiple choice questions, and the rest from short answer questions (a paragraph or dot points or a diagram). There will be some choice for the short answer questions.
All the lecture and practical material is examinable. A non-programmable scientific calculator will be required in the exam but dictionaries are not allowed.
On successful completion you will be able to:
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
- Identify the components of the neural and endocrine systems that maintain energy balance in the human body
- Critically evaluate information and form logical arguments supported by experimental evidence
Delivery and Resources
There will be two lectures each week and these will be on Monday at 11 am in 14 Sir Christopher Ondaatje Ave - T3 Theatre and Tuesday at 8 am in 23 Wallys Wlk - T2. All lectures will be recorded and available on iLean.
Each week internal students are expected attend one practical class at either Tuesday from 1 pm to 5 pm or Tuesday from 10 am until 1 pm. External students need to attend all four days of the on-campus session. All practical classes will be in 4 Wallys WLK Science labs (F7B 102, 105 and 110).
Practical sessions for external students will be held on Saturday 24th and Sunday 25th March and on Wednesday 18th and Thursday 19th of April in the 4 Wallys WLK Science labs (F7B 102, 105 and 110).
The textbook for this unit is “Principals of Human Physiology” 6th edition by Cindy L Stanfield, published by Pearson. You can subscribe to the new digital version (6th addition) at
http://www.pearson.com.au/9781292156491 and you do not need MasteringA&P.
However, much of the material covered in BIOL376 is not available in text books. When this is the case, I have included relevant references in the lecture graphics.
Your iLearn site will contain the unit outline, lecture graphics, lecture notes, practical manual, a link to the Active Learning Platform (previously Echo), announcements and discussion areas. Later, marks for in semester assessments tasks will be available in Grade Book. Please check this site and your student email regularly
Unit Schedule
Lecture Timetable 2018
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Week |
Beginning on |
Lecture |
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1 |
26/2 |
1. Short term control of BP |
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2. Long term control of BP |
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2 |
5/3 |
3. Hypertension |
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4. Exercise I |
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3 |
12/3 |
5. Exercise II |
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6. Acid base regulation in the body |
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4 |
19/3 |
7. Disturbances acid/base balance |
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8. Hormones, signal transduction and cell messengers |
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5 |
26/3 |
9. Regulation of plasma K+ concentration |
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10. Regulation of plasma Ca2+ concentration |
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6 |
2/4 |
11. Neuroendocrinology |
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12. Regulation of plasma glucose concentration |
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7 |
9/4 |
Catch up lecture |
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Mid-semester test in practical session |
Study break: 16/4-27/4
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8 |
30/4 |
13. Stress hormones |
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14. The obesity epidemic and energy balance |
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9 |
7/5 |
15. Homeostatic control of appetite |
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16. Reward systems and hedonic eating |
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10 |
14/5 |
17. Genetics of obesity |
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18. Foetal effects and epigenetics(Dr Jess Buxton; NS talks) |
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11 |
21/5 |
19. Protein and energy balance |
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20. The microbiota |
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12 |
28/5 |
21. TBA |
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22. TBA |
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13 |
4/6 |
no lecture |
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no lecture |
Internal Practical Timetable 2018
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Wk |
Practical |
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1 |
no practical |
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2 |
Introduction to BIOL76 and organize seminar groups Discuss safety and protocol for the exercise prac, organize subjects and sign consent forms, practice blood pressure measurement, begin experiments |
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3 |
The effect of exercise on the cardiovascular system- complete experiments and analyze results |
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4 |
Acid-base balance tutorial (calculator with logs needed for this prac) Discuss ethics and protocol for the acid base prac, organize subjects and sign consent forms |
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5 |
The effect of net acid or base ingestion on the pH and the hydrogen ion and bicarbonate excretion in the urine (lab coats) |
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6 |
Analysis of acid base practical results |
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7 |
Mid-semester test |
Study break: 16/4-27/4
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8 |
Revision of the mid-semester test and case studies; collection of tubes for saliva (essay submission 30/4 internal and external students) |
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9 |
Student Seminars |
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10 |
Student seminars |
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11 |
Salivary cortisol (lab coats), lactose/fructose intolerance and case studies plus tutorial on plasma glucose immediately after a meal and during a fast |
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12 |
Salivary cortisol results and revision session based on the 2017 exam paper |
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13 |
No practical
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External Practical Timetable 2018
Practical sessions for external students will be held on Saturday 24 and Sunday 25 March and on Wednesday and Thursday the 18 & 19 April. The classes start promptly at 9.00 am and will be held in 4 WW-110 Science lab (F7B 110).
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Saturday 24/03/2018 |
Wednesday 18/04/2018 |
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Introduction |
Mid-semester test |
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Acid-base balance tutorial and discuss ethics and protocol for the acid base pracs, organise subjects and sign consent forms |
Cortisol in the saliva |
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The effect of net acid or base ingestion on the pH, hydrogen ion and bicarbonate excretion in the urine (lab coats) |
Case studies |
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Sunday 25/03/2018 |
Thursday 19/04/2018 |
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Analysis of the acid base prac results
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Student Seminars |
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Exercise and the cardiovascular system |
Analysis of cortisol results |
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Lactose and fructose intolerance |
Please note that for external students, the mid-semester test on the cardiovascular and renal systems, which is worth 10% of the marks, is on Wednesday, 18/04/2018.
Policies and Procedures
Macquarie University policies and procedures are accessible from Policy Central (https://staff.mq.edu.au/work/strategy-planning-and-governance/university-policies-and-procedures/policy-central). Students should be aware of the following policies in particular with regard to Learning and Teaching:
- Academic Appeals Policy
- Academic Integrity Policy
- Academic Progression Policy
- Assessment Policy
- Fitness to Practice Procedure
- Grade Appeal Policy
- Complaint Management Procedure for Students and Members of the Public
- Special Consideration Policy (Note: The Special Consideration Policy is effective from 4 December 2017 and replaces the Disruption to Studies Policy.)
Undergraduate students seeking more policy resources can visit the Student Policy Gateway (https://students.mq.edu.au/support/study/student-policy-gateway). It is your one-stop-shop for the key policies you need to know about throughout your undergraduate student journey.
If you would like to see all the policies relevant to Learning and Teaching visit Policy Central (https://staff.mq.edu.au/work/strategy-planning-and-governance/university-policies-and-procedures/policy-central).
Student Code of Conduct
Macquarie University students have a responsibility to be familiar with the Student Code of Conduct: https://students.mq.edu.au/study/getting-started/student-conduct
Results
Results shown in iLearn, or released directly by your Unit Convenor, are not confirmed as they are subject to final approval by the University. Once approved, final results will be sent to your student email address and will be made available in eStudent. For more information visit ask.mq.edu.au.
Student Support
Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/
Learning Skills
Learning Skills (mq.edu.au/learningskills) provides academic writing resources and study strategies to improve your marks and take control of your study.
Student Services and Support
Students with a disability are encouraged to contact the Disability Service who can provide appropriate help with any issues that arise during their studies.
Student Enquiries
For all student enquiries, visit Student Connect at ask.mq.edu.au
IT Help
For help with University computer systems and technology, visit http://www.mq.edu.au/about_us/offices_and_units/information_technology/help/.
When using the University's IT, you must adhere to the Acceptable Use of IT Resources Policy. The policy applies to all who connect to the MQ network including students.
Graduate Capabilities
Creative and Innovative
Our graduates will also be capable of creative thinking and of creating knowledge. They will be imaginative and open to experience and capable of innovation at work and in the community. We want them to be engaged in applying their critical, creative thinking.
This graduate capability is supported by:
Learning outcomes
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Assessment tasks
- Essay
- Seminar
Capable of Professional and Personal Judgement and Initiative
We want our graduates to have emotional intelligence and sound interpersonal skills and to demonstrate discernment and common sense in their professional and personal judgement. They will exercise initiative as needed. They will be capable of risk assessment, and be able to handle ambiguity and complexity, enabling them to be adaptable in diverse and changing environments.
This graduate capability is supported by:
Learning outcomes
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
- Formal exam
Commitment to Continuous Learning
Our graduates will have enquiring minds and a literate curiosity which will lead them to pursue knowledge for its own sake. They will continue to pursue learning in their careers and as they participate in the world. They will be capable of reflecting on their experiences and relationships with others and the environment, learning from them, and growing - personally, professionally and socially.
This graduate capability is supported by:
Learning outcome
- Synthesize information from the scientific literature for presentation in written and oral formats
Assessment tasks
- Essay
- Seminar
Discipline Specific Knowledge and Skills
Our graduates will take with them the intellectual development, depth and breadth of knowledge, scholarly understanding, and specific subject content in their chosen fields to make them competent and confident in their subject or profession. They will be able to demonstrate, where relevant, professional technical competence and meet professional standards. They will be able to articulate the structure of knowledge of their discipline, be able to adapt discipline-specific knowledge to novel situations, and be able to contribute from their discipline to inter-disciplinary solutions to problems.
This graduate capability is supported by:
Learning outcomes
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
- Identify the components of the neural and endocrine systems that maintain energy balance in the human body
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
- Mid semester test
- Essay
- Seminar
- Formal exam
Critical, Analytical and Integrative Thinking
We want our graduates to be capable of reasoning, questioning and analysing, and to integrate and synthesise learning and knowledge from a range of sources and environments; to be able to critique constraints, assumptions and limitations; to be able to think independently and systemically in relation to scholarly activity, in the workplace, and in the world. We want them to have a level of scientific and information technology literacy.
This graduate capability is supported by:
Learning outcomes
- Explain how the cardiovascular, renal, and respiratory systems contribute to homeostasis
- Identify the components of the neural and endocrine systems that maintain energy balance in the human body
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
- Mid semester test
- Essay
- Seminar
- Formal exam
Problem Solving and Research Capability
Our graduates should be capable of researching; of analysing, and interpreting and assessing data and information in various forms; of drawing connections across fields of knowledge; and they should be able to relate their knowledge to complex situations at work or in the world, in order to diagnose and solve problems. We want them to have the confidence to take the initiative in doing so, within an awareness of their own limitations.
This graduate capability is supported by:
Learning outcomes
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
Effective Communication
We want to develop in our students the ability to communicate and convey their views in forms effective with different audiences. We want our graduates to take with them the capability to read, listen, question, gather and evaluate information resources in a variety of formats, assess, write clearly, speak effectively, and to use visual communication and communication technologies as appropriate.
This graduate capability is supported by:
Learning outcomes
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
- Analyze experimental data and interpret physiological significance
- Synthesize information from the scientific literature for presentation in written and oral formats
- Critically evaluate information and form logical arguments supported by experimental evidence
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
- Essay
- Seminar
- Formal exam
Engaged and Ethical Local and Global citizens
As local citizens our graduates will be aware of indigenous perspectives and of the nation's historical context. They will be engaged with the challenges of contemporary society and with knowledge and ideas. We want our graduates to have respect for diversity, to be open-minded, sensitive to others and inclusive, and to be open to other cultures and perspectives: they should have a level of cultural literacy. Our graduates should be aware of disadvantage and social justice, and be willing to participate to help create a wiser and better society.
This graduate capability is supported by:
Learning outcomes
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
Socially and Environmentally Active and Responsible
We want our graduates to be aware of and have respect for self and others; to be able to work with others as a leader and a team player; to have a sense of connectedness with others and country; and to have a sense of mutual obligation. Our graduates should be informed and active participants in moving society towards sustainability.
This graduate capability is supported by:
Learning outcomes
- Perform experiments safely with human subjects
- Practice measurements of physiological responses in human subjects
Assessment tasks
- Exercise assignment
- Acid /base balance assignment
Changes from Previous Offering
Compared to the 2017 version in 2018 there has been a change to the order of the lectures and practical sessions and one more assignment has been added.