CHEM3801 is a 10 credit point unit requiring 150 hours of work over the semester (formal contact hours and self study time). This is an average of 10 hours of work per week over each of the 15 weeks of semester. For students with weaker chemistry backgrounds, more time per week will likely be needed to perform satisfactorily in this unit. Formal contact hours for CHEM3801 consist of 2 hours of lectures and a 1-hour interactive tutorial (SGTA) per week, along with 7 x 4-hour laboratory classes throughout semester. Students are expected to participate in all lectures, tutorials and laboratory classes. Active participation by students in all of these activities will be essential for success in the unit.
The unit will cover 2 hours of lecture material each week. This will consist of a mixture of pre-recorded lectures and interactive (live) lectures. Some lecture material will be available on the unit web site, while other material will be provided during the lecture classes. You should use these lectures as a starting point and supplement their content with material from the text book, the scientific literature and from other online sources. Much of the unit content builds on content covered in previous weeks, so it will be essential to keep up to date with the lecture material throughout the semester. A 1-hour mid-semester test (worth 15%) will be run in Week 8 during the allocated lecture time. This test will cover all course material up to and including Week 7.
Interactive Tutorials (SGTAs)
A 1-hour interactive tutorial (SGTA) will be held each week. This is your opportunity to interact directly with the teaching staff, to ask lots of pertinent questions and to identify any weaknesses or clarify misconceptions you may have. Learning is an active process, and as such, you must engage with the material. This means reading the textbook (and beyond) before and after lectures, attempting the assignment questions and discussing the concepts with your classmates and lecturers. Do not be afraid to ask questions – everyone benefits from a robust and open discussion of the topics. Five short quizzes (each worth 1% of the unit total) will also be run throughout semester. The quizzes may include any material that has been covered in the unit up to that point, so you are expected to keep up to date with lectures and to revise course material each week. The quizzes are designed to help you to learn continuously and to identify what you understand and the areas that you need to spend more time on, with minimal assessment penalty.
Laboratory classes will be conducted in small teams and require a highly collaborative and investigative approach. You will be designing and synthesising a series of sulfonamide antibiotics and subsequently testing them for antibacterial activity to determine the important features for their antibacterial activity. This laboratory work is designed to give real-world experience in research by involving you in the design of the experiments, using literature procedures as a guide, and troubleshooting to identify the best experimental conditions. The classes will emphasise the importance of teamwork and being well prepared and efficient. You will need to be fully aware of safety procedures, proper recording and reporting of raw data and interpretation of results. This will require an analytical and inquisitive approach. The first (dry) laboratory class starts in Week 1, where you will meet your fellow team members, plan your synthetic routes and complete risk assessments. There will then be 5 wet labs sessions run in two streams (Group A and Group B) on alternating weeks, starting in Weeks 2/3. The final (dry) laboratory class in Week 13 will bring all the team back together to discuss their results and to finalise the laboratory reports. To maximise the amount of wet lab time available to complete the experiments, you will need to be highly organised and to have prepared thoroughly BEFORE entering the laboratory. If you are not able to "hit the ground running" each laboratory class, you will almost certainly run out of time by the end of semester.
Unit Web Page
The web page for this unit can be found at ilearn.mq.edu.au.
Login with your MQ student ID number and password, then follow the prompts to "CHEM3801/6801 Medicinal Chemistry."
During semester, the CHEM3801/6801 iLearn site will be used to communicate important information to you. It is your responsibility to regularly check the iLearn site for important announcements and updates.
Unit Text Book
"An Introduction to Medicinal Chemistry" by Graham L. Patrick, Sixth Edition, Oxford University Press 2017.
The text book may be purchased from www.booktopia.com.au or other book shops. Limited copies of the text book are also available in the MQ Library.