Unit convenor and teaching staff |
Unit convenor and teaching staff
Unit Convenor, Lecturer and Tutor
Albert Lee
Contact via email
Consultation by appointment
Course Director
Marina Junqueira Santiago
Contact via email
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Credit points |
Credit points
10
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Prerequisites |
Prerequisites
140cp at 1000 level or above including [(CBMS104 or BMOL1001) and (MEDI219 or MEDI2200)] or [(CBMS107 or CHEM1001) and (BIOL206 or BIOL2110) and (CBMS202 or BMOL2401) and (MEDI2201)]
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Corequisites |
Corequisites
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Co-badged status |
Co-badged status
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Unit description |
Unit description
This unit represents the final unit in the Biochemistry stream of units within the Bachelor of Clinical Science. Key concepts in genetics, cell biology and biochemistry, which are fundamental to our understanding of human biology, diseases and medicine are examined. You will learn about signal transduction, cytoskeletal dynamics, mitochondrial dysfunction, protein metabolism, stem cells and molecular targeted therapies. You will explore cellular pathways and processes involved in cellular homeostasis, and perturbations and defects that lead to disease (e.g. cancer and neurodegenerative disorders). You will participate in practical classes that complement the lecture series and allow you to consolidate and apply conceptual elements to help shape your understanding. You will be required to use laboratory techniques including analysis of signalling cascades, and microscopy. |
Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates
On successful completion of this unit, you will be able to:
Grade descriptors and other information concerning grading are contained in the Macquarie University Assessment Policy.
All final grades are determined by a grading committee, in accordance with the Macquarie University Assessment Policy, and are not the sole responsibility of the Unit Convenors.
Students will be awarded a final grade and a mark which must correspond to the grade descriptors specified in the Assessment Procedure (clause 128).
To pass this unit, students must demonstrate sufficient evidence of achievement of the learning outcomes, meet any ungraded requirements, and achieve a final mark of 50 or better.
Further details for each assessment task will be available on iLearn.
Unless a Special Consideration request has been submitted and approved, a 5% penalty (of the total possible mark) will be applied each day a written assessment is not submitted, up until the 7th day (including weekends). After the 7th day, a grade of ‘0’ will be awarded even if the assessment is submitted. Submission time for all written assessments is set at 11.55 pm. A one-hour grace period is provided to students who experience a technical concern.
For example:
Number of days (hours) late | Total possible marks | Deduction | Raw mark | Final mark |
---|---|---|---|---|
1 day (1-24 hours) | 100 | 5 | 75 | 70 |
2 days (24-48 hours) | 100 | 10 | 75 | 65 |
3 days (48-72 hours) | 100 | 15 | 75 | 60 |
7 days (144-168 hours) | 100 | 35 | 75 | 40 |
>7 days (>168 hours) | 100 | - | 75 | 0 |
For any late submissions of time-sensitive tasks, such as scheduled tests/exams, performance assessments/presentations, and/or scheduled practical assessments/labs, students need to submit an application for Special Consideration.
If you are unable to complete an assessment task on or by the specified date due to circumstances that are unexpected, unavoidable, significantly disruptive and beyond your control, you may apply for special consideration in accordance with the Special Consideration Policy. Applications for special consideration must be supported by appropriate evidence and submitted via ask.mq.edu.au.
Name | Weighting | Hurdle | Due |
---|---|---|---|
Ongoing Weekly Quizzes | 15% | No | Ongoing |
Laboratory Report and Assignments | 35% | No | Week 7, 9, 13 |
Final examination | 50% | No | Exam period |
Assessment Type 1: Quiz/Test
Indicative Time on Task 2: 10 hours
Due: Ongoing
Weighting: 15%
Weekly multiple choice and short answer quizzes to assess lecture content.
Assessment Type 1: Lab report
Indicative Time on Task 2: 30 hours
Due: Week 7, 9, 13
Weighting: 35%
A three part assessment that includes (1) the group submission of a short scientific report that contextualises the experimental observations and results acquired during practical classes; (2) submission of an individual bioinformatics assignment; and (3) submission of an individual laboratory report that documents accurately and comprehensively all work undertaken within the practical classes.
Assessment Type 1: Examination
Indicative Time on Task 2: 30 hours
Due: Exam period
Weighting: 50%
The final exam will be composed of a mixture of questions that include MCQs, short and long answer questions. All content will be assessed.
1 If you need help with your assignment, please contact:
2 Indicative time-on-task is an estimate of the time required for completion of the assessment task and is subject to individual variation
Technology Used
Active participation in the learning activities throughout the unit will generally require students to have access to a tablet, laptop or similar device. Students who do not own their own laptop computer may borrow one from the university library.
Required Unit Materials
All students are required to wear closed shoes and a lab coat/gown to attend practical classes.
Recommended Readings
Unit readings for this unit are available via the iLearn and university library website.
The prescribed textbook for this unit is
Lodish, H (2021) Molecular Cell Biology (9th Edition) Macmillan Learning OR
Alberts, B (2022) Molecular Biology of the Cell (7th Edition). W W Norton & Company
Other recommended texts that are available at the library
Week | Lecture Topic | Delivered by | Tutorial | Practical | Assessment |
1 | Overview, Cell Signaling Basics, Techniques in biology | Albert Lee/iLearn | Tutorial 1 (Stream A) | Practical 1 (Stream B) | Online Quiz |
2 | Genetics, Genomics and Genetic Therapies | Jenn Fifita | Tutorial 1 (Stream B) | Practical 1 (Stream A) | Online Quiz |
3 | Cell Cycle dysregulation in cancer | Lucinda McRobb | Tutorial 2 (Stream A) | Practical 2 (Stream B) | Online Quiz |
4 | DNA damage and repair | Lucinda McRobb | Tutorial 2 (Stream B) | Practical 2 (Stream A) | Online Quiz |
5 | Signaling pathways in health and disease | Esther Lim | Tutorial 3 (Stream A) | Practical 3 (Stream B) | Online Quiz |
6 | Apoptosis and Necrosis Cell survival pathways (UPS and autophagy) | Albert Lee/Shu Yang | Tutorial 3 (Stream B) | Practical 3 (Stream A) | Online Quiz |
7 | Transcription regulation, RNA processing and Transcriptomics in human disease | Albert Lee | Tutorial 4 (Stream A) | Practical 4 (Stream B) | Online Quiz & Bioinformatics Assignment |
RECESS | |||||
8 | Protein Metabolism and Proteomics | Albert Lee | Tutorial 4 (Stream B) | Practical 4 (Stream A) | |
9 | Mitochondrial dysfunction and antioxidant therapies | Albert Lee | Tutorial 5 (Stream A) | Practical 5 (Stream B) | Group Lab Report |
10 | Transgenic animals | Marco Morsch | Tutorial 5 (Stream B) | Practical 5 (Stream A) | |
11 | Neuroprotection and Microglia Stem Cells and Regeneration Therapies | Roger Chung | Tutorial 6 (Stream A) | Practical 6 (Stream B) | |
12 | Translating basic discoveries to pharma and clinic | Albert Lee | Tutorial 6 (Stream B) | Practical 6 (Stream A) | |
13 | Revision | Albert Lee | Revision | Lab book |
Macquarie University policies and procedures are accessible from Policy Central (https://policies.mq.edu.au). Students should be aware of the following policies in particular with regard to Learning and Teaching:
Students seeking more policy resources can visit Student Policies (https://students.mq.edu.au/support/study/policies). It is your one-stop-shop for the key policies you need to know about throughout your undergraduate student journey.
To find other policies relating to Teaching and Learning, visit Policy Central (https://policies.mq.edu.au) and use the search tool.
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Results published on platform other than eStudent, (eg. iLearn, Coursera etc.) or released directly by your Unit Convenor, are not confirmed as they are subject to final approval by the University. Once approved, final results will be sent to your student email address and will be made available in eStudent. For more information visit ask.mq.edu.au or if you are a Global MBA student contact globalmba.support@mq.edu.au
At Macquarie, we believe academic integrity – honesty, respect, trust, responsibility, fairness and courage – is at the core of learning, teaching and research. We recognise that meeting the expectations required to complete your assessments can be challenging. So, we offer you a range of resources and services to help you reach your potential, including free online writing and maths support, academic skills development and wellbeing consultations.
Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/
The Writing Centre provides resources to develop your English language proficiency, academic writing, and communication skills.
The Library provides online and face to face support to help you find and use relevant information resources.
Macquarie University offers a range of Student Support Services including:
Got a question? Ask us via AskMQ, or contact Service Connect.
For help with University computer systems and technology, visit http://www.mq.edu.au/about_us/offices_and_units/information_technology/help/.
When using the University's IT, you must adhere to the Acceptable Use of IT Resources Policy. The policy applies to all who connect to the MQ network including students.
Social inclusion at Macquarie University is about giving everyone who has the potential to benefit from higher education the opportunity to study at university, participate in campus life and flourish in their chosen field. The University has made significant moves to promote an equitable, diverse and exciting campus community for the benefit of staff and students. It is your responsibility to contribute towards the development of an inclusive culture and practice in the areas of learning and teaching, research, and service orientation and delivery. As a member of the Macquarie University community, you must not discriminate against or harass others based on their sex, gender, race, marital status, carers' responsibilities, disability, sexual orientation, age, political conviction or religious belief. All staff and students are expected to display appropriate behaviour that is conducive to a healthy learning environment for everyone.
In the Faculty of Medicine, Health and Human Sciences, professionalism is a key capability embedded in all our courses.
As part of developing professionalism, students are expected to attend all small group interactive sessions, including clinical, practical, laboratory, work-integrated learning (e.g., PACE placements), and team-based learning activities. Some learning activities are recorded (e.g., face-to-face lectures), however you are encouraged to avoid relying upon such material as they do not recreate the whole learning experience and technical issues can and do occur. As an adult learner, we respect your decision to choose how you engage with your learning, but we would remind you that the learning opportunities we create for you have been done so to enable your success, and that by not engaging you may impact your ability to successfully complete this unit. We equally expect that you show respect for the academic staff who have worked hard to develop meaningful activities and prioritise your learning by communicating with them in advance if you are unable to attend a small group interactive session.
Another dimension of professionalism is having respect for your peers. It is the right of every student to learn in an environment that is free of disruption and distraction. Please arrive to all learning activities on time, and if you are unavoidably detained, please join the activity as quietly as possible to minimise disruption. Phones and other electronic devices that produce noise and other distractions must be turned off prior to entering class. Where your own device (e.g., laptop) is being used for class-related activities, you are asked to close down all other applications to avoid distraction to you and others. Please treat your fellow students with the utmost respect. If you are uncomfortable participating in any specific activity, please let the relevant academic know.
Unit information based on version 2023.01R of the Handbook