Unit Guide

General Information

Unit convenor and teaching staff	Unit convenor and teaching staff Paul Haynes paul.haynes@mq.edu.au
Credit points	Credit points 10
Prerequisites	Prerequisites Admission to MRes
Corequisites	Corequisites
Co-badged status	Co-badged status Mols8212
Unit description	Unit description Proteomics is the study of protein expression in living systems, considered in a functional context. This allows us to better understand how protein networks become dysfunctional, which in turn enables the manipulation of protein functions and cellular phenotypes through environmental or genetic intervention, or the use of drug treatment. This unit covers the principles and applications of proteomic techniques, and assumes basic knowledge of protein electrophoresis and mass spectrometry. Topics include: a detailed study of advanced techniques, instrumentation and protein identification software in mass spectrometry; two-dimensional differential gel electrophoresis; label-free and isotope-labelling quantitation in proteomics; application of different types of peptide- and protein-based shotgun proteomics approaches; multiplexed reaction monitoring: data independent acquisition; and characterisation of protein post-translational modifications including phosphorylation and glycosylation. Students must attend a compulsory one week laboratory session during the semester break.

Important Academic Dates

Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates

Learning Outcomes

On successful completion of this unit, you will be able to:

ULO1: Process scientific data and prepare written work in formats suitable for publication in peer-reviewed scientific journals.
ULO2: Communicate to their peers a summary of a recent publication in a contemporary area of proteomics, and produce their own peer-review of that publication.
ULO3: Develop skills in critical thinking and analysis, and written and oral presentation of scientific information.
ULO4: Extract and summarise from the scientific literature information required to develop a research plan within a relevant area of proteomics.
ULO5: Describe the basis of technologies used in proteomics, and exhibit sound knowledge of how to apply proteomics techniques to answer biological questions.
ULO6: Explain the chemical, biochemical and biophysical processes involved in proteomics, and demonstrate proficiency in a range of practical proteomics techniques.

General Assessment Information

Requirements to Pass this Unit

To pass this unit you must:

Attempt all assessments, and
Achieve a total mark equal to or greater than 50%,

Late Assessment Submission Penalty

Unless a Special Consideration request has been submitted and approved, a 5% penalty (of the total possible mark of the task) will be applied for each day a written report or presentation assessment is not submitted, up until the 7^th day (including weekends). After the 7^th day, a grade of ‘0’ will be awarded even if the assessment is submitted. The submission time for all uploaded assessments is 11:55 pm. A 1-hour grace period will be provided to students who experience a technical concern.

Assessments where Late Submissions will be accepted

This applies to all submitted assessments.

Special Consideration

For any late submission of time-sensitive tasks, such as scheduled tests/exams, performance assessments/presentations, and/or scheduled practical assessments/labs, please apply for Special Consideration.

The Special Consideration Policy aims to support students who have been impacted by short-term circumstances or events that are serious, unavoidable and significantly disruptive, and which may affect their performance in assessment. If you experience circumstances or events that affect your ability to complete the assessments in this unit on time, please inform the convenor and submit a Special Consideration request through ask.mq.edu.au.

Assessment Tasks

Name	Weighting	Hurdle	Due
Oral Workshop Presentation	15%	No	Various dates throughout the semester
Continuing assessment	5%	No	weekly
Final Exam	40%	No	Exam period
Practical Report	20%	No	8th October
Mid-semester test	5%	No	week 9
Mini-Review Essay	15%	No	Friday 6th September

Oral Workshop Presentation

Assessment Type ¹: Presentation
Indicative Time on Task ²: 16 hours
Due: Various dates throughout the semester
Weighting: 15%

Choose one publication from the Workshop Papers List (on a first-come first-served basis), which is found on a wiki on the iLearn site. Present your critique of the topic as a short Powerpoint seminar. Aim for 10-12 min talking (15 minutes max), and there will be time for questions. We may adjust that schedule depending on class numbers. Participation in all other group’s topics contributes to your final mark Perform your own peer-review of your chosen paper - tell us whether you think this paper should have been published and why. Look up other relevant literature so you can discuss your chosen paper in context rather than in isolation. The research workshop presentation will now be accepted as a video presentation uploaded in advance to youtube. It must include figures, graphics, text (and some footage of the presenter). You can either record straight to video camera, or use software such as iMovie or Windows Movie Maker.