Students

BMOL6202 – Macromolecules

2026 – Session 2, In person-scheduled-weekday, North Ryde

General Information

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Unit convenor and teaching staff Unit convenor and teaching staff
Bhumika Shah
Credit points Credit points
10
Prerequisites Prerequisites
Admission to GradDipBiotech or MBiotech
Corequisites Corequisites
Co-badged status Co-badged status
BMOL3202
Unit description Unit description

This unit outlines molecular principles underlying macromolecules and nano-materials that find a wide range of applications from nanotechnology, biomedical research, to bio-engineering. Practices common in these fields to design, prepare, synthesise and then isolate new materials will be emphasized. Molecular properties leading to the 3D shape of macromolecules will be reviewed. Contemporary structural and imaging based methods to view and characterise macromolecules, both natural and synthetic, will be examined. In particular, attention will be given to the chemical, biochemical and structural characterisation of the building blocks of the living world including nucleic acids, proteins, and polysaccharides. Recent advances and landmark reports from the current literature will be examined. The unit will be delivered through workshops, seminars, lab work and project-based learning.

Learning in this unit enhances student understanding of global challenges identified by the United Nations Sustainable Development Goals (UNSDGs) Good Health and Well Being; Quality Education; Industry, Innovation and Infrastructure

Important Academic Dates

Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates

Learning Outcomes

On successful completion of this unit, you will be able to:

  • ULO1: Describe and apply the underlying principles for synthesising and engineering macromolecules and other synthetic particle-based nanomaterials. Apply this knowledge to design and conduct experiments to synthesise macromolecules in the laboratory.
  • ULO2: Describe bio-macromolecular forms and architectures (size/shape) for proteins, sugars and nucleotides.
  • ULO3: Apply basic concepts from thermodynamics and kinetics to interpret molecular mechanisms of macromolecule systems.
  • ULO4: Describe the principles of contemporary analytical tools to image and characterise the structural features of bio-macromolecules and synthetic macromolecules. Utilise these techniques to collect experimental data on one or more macromolecule.
  • ULO5: Interpret and draw sound conclusions from analytical and biophysical data.
  • ULO6: Extract and interpret information from a variety of sources concerning macromolecules, including the contemporary scientific literature.

General Assessment Information

A. Assessment Release

  • Lab book: specifications to be released no later than 5th August, 2026
  • Case Study: details to be released by 10th August, 2026

B. Requirements to Pass this Unit

To pass this unit, you need to:

  • Achieve a total mark equal to or greater than 50% across all assessments

C. Participation

We strongly encourage all students to actively participate in all learning activities. Regular engagement is crucial for your success in this unit, as these activities provide opportunities to deepen your understanding of the material, collaborate with peers, and receive valuable feedback from instructors, to assist in completing the unit assessments. Your active participation not only enhances your own learning experience but also contributes to a vibrant and dynamic learning environment for everyone.

D. Late Assessment Submission Penalty 

Unless a Special Consideration request has been submitted and approved, a 5% penalty (of the total possible mark of the task) will be applied for each day a written report or presentation assessment is not submitted, up until the 7th day (including weekends). After the 7th day, a grade of ‘0’ will be awarded even if the assessment is submitted. The submission time for all uploaded assessments is 11:55 pm. A 1-hour grace period will be provided to students who experience technical concerns. For any late submission of time-sensitive tasks, such as scheduled tests/exams, performance assessments/presentations, and/or scheduled practical assessments/labs, please apply for Special Consideration. For example, if the assignment is worth 8 marks (of the entire unit) and your submission is late by 19 hours (or 23 hours 59 minutes 59 seconds), 0.4 marks (5% of 8 marks) will be deducted. If your submission is late by 24 hours (or 47 hours 59 minutes 59 seconds), 0.8 marks (10% of 8 marks) will be deducted, and so on.

E. Assessments where Late Submissions will be accepted: 

In this unit, late submissions will be accepted as follows: 

LABORATORY BOOK - Yes, standard late penalty applies (unless Special Consideration is granted). 

CASE STUDY ORAL PRESENTATION - NO, unless Special Consideration is granted. 

F. Special Consideration

The Special Consideration Policy aims to support students who have been impacted by short-term circumstances or events that are serious, unavoidable and significantly disruptive, and which may affect their performance in assessment. If you experience circumstances or events that affect your ability to complete the assessments in this unit on time, please inform the convenor and submit a Special Consideration request through https://connect.mq.edu.au.

Assessment Tasks

Name Weighting Hurdle Due Groupwork/Individual Short Extension AI Approach
Lab book 40% No 06/10/2026 Individual Yes Open
Case study 20% No 26/10/2026 Individual and Group No Open
Final Exam 40% No Exam Period Individual No Observed

Lab book

Assessment Type 1: Professional task
Indicative Time on Task 2: 34 hours
Due: 06/10/2026
Weighting: 40%
Groupwork/Individual: Individual
Short extension 3: Yes
AI Approach: Open

You will submit a completed lab book containing experimental results and evidence of consistent data collection throughout laboratory classes. Your work will document procedures, observations, and outcomes clearly. This task builds accuracy, scientific record‑keeping, and practical laboratory skills essential for professional and academic practice.


On successful completion you will be able to:
  • Describe and apply the underlying principles for synthesising and engineering macromolecules and other synthetic particle-based nanomaterials. Apply this knowledge to design and conduct experiments to synthesise macromolecules in the laboratory.
  • Apply basic concepts from thermodynamics and kinetics to interpret molecular mechanisms of macromolecule systems.
  • Describe the principles of contemporary analytical tools to image and characterise the structural features of bio-macromolecules and synthetic macromolecules. Utilise these techniques to collect experimental data on one or more macromolecule.
  • Interpret and draw sound conclusions from analytical and biophysical data.

Case study

Assessment Type 1: Presentation task
Indicative Time on Task 2: 20 hours
Due: 26/10/2026
Weighting: 20%
Groupwork/Individual: Individual and Group
Short extension 3: No
AI Approach: Open

You will work in small groups to prepare a presentation on a contemporary macromolecule, reflecting communication practices used in scientific fields. Together, you’ll research, organise, and present key information. This task develops your scientific literacy, teamwork, and ability to communicate complex concepts clearly. Half of the marks are for the group and half the marks are for your individual contribution.


On successful completion you will be able to:
  • Describe bio-macromolecular forms and architectures (size/shape) for proteins, sugars and nucleotides.
  • Describe the principles of contemporary analytical tools to image and characterise the structural features of bio-macromolecules and synthetic macromolecules. Utilise these techniques to collect experimental data on one or more macromolecule.
  • Extract and interpret information from a variety of sources concerning macromolecules, including the contemporary scientific literature.

Final Exam

Assessment Type 1: Examination
Indicative Time on Task 2: 20 hours
Due: Exam Period
Weighting: 40%
Groupwork/Individual: Individual
Short extension 3: No
AI Approach: Observed

You will undertake a final examination during the formal examination period.


On successful completion you will be able to:
  • Describe and apply the underlying principles for synthesising and engineering macromolecules and other synthetic particle-based nanomaterials. Apply this knowledge to design and conduct experiments to synthesise macromolecules in the laboratory.
  • Describe bio-macromolecular forms and architectures (size/shape) for proteins, sugars and nucleotides.
  • Apply basic concepts from thermodynamics and kinetics to interpret molecular mechanisms of macromolecule systems.
  • Describe the principles of contemporary analytical tools to image and characterise the structural features of bio-macromolecules and synthetic macromolecules. Utilise these techniques to collect experimental data on one or more macromolecule.
  • Interpret and draw sound conclusions from analytical and biophysical data.

1 If you need help with your assignment, please contact:

  • the academic teaching staff in your unit for guidance in understanding or completing this type of assessment
  • Academic Success for academic skills support.

2 Indicative time-on-task is an estimate of the time required for completion of the assessment task and is subject to individual variation.

3 An automatic short extension is available for some assessments. Apply through the Service Connect Portal.

Delivery and Resources

Week 1 Classes: As detailed in the Unit Schedule below, the two 1-hour lectures in Week 1 are pre-recorded and will be uploaded to iLearn. There are no on-campus activities in Week 1. 

Lectures: There are two lectures per week, as per the university timetable. All lectures are delivered on campus (except in week 1) and will be recorded. All lecture material will be available on iLearn.

Laboratory Sessions (Wet-lab): 3-hour laboratory sessions are scheduled according to the timetable. There are two timetabled sessions available.

Practicals 1 - 4 will be held on campus at the Science labs in 14 Sir Christopher Ondaatje Ave (E7B) 349+350 Science Lab. In total, there are FOUR lab sessions held in weeks 2, 4, 6 and 8. Participation in all four laboratory sessions is required to collect data to complete the Lab book assessment (40%). If you cannot attend, you must submit a Special Consideration request for your absence to be considered.

** Students must bring their own lab coats to enter the labs. It is also recommended that students bring their own safety glasses. However, these will be provided if students do not have their own safety glasses. Other PPE will be provided.

SGTA/Workshop Sessions (3 hrs): SGTA sessions will be held on campus, alongside the five scheduled workshop sessions (total 3 hrs: 1 hr SGTA + 2 hrs Workshops) in Weeks 3, 5, 7, 10, and 12. Workshop 1 will support the Laboratory Book assessment. Workshops 2-4 will include a non-assessable quiz to encourage engagement and provide early feedback. The case study oral presentations are to be delivered during Workshop 5.

Case study presentations: Will be held during the scheduled SGTA/Workshop session in Week 12. A short (~10-minute) presentation is to be delivered in small groups on a contemporary macromolecule. Half of the marks are for the group, and half are for your individual contribution. If you cannot attend, a Special Consideration request must be submitted for your absence to be considered.

**Students are required to bring their own laptops to on-campus workshop sessions. Please ensure your laptop is fully charged, as power points may not be available to all students. If you require a laptop loan, this can be arranged PRIOR to the workshop session by contacting the unit convenor. 

Textbooks: Reading material and required text will be provided by your lecturer. A list of suggested reading material and texts will be made available on iLearn and on the library website at https://libguides.mq.edu.au/leganto.

Methods of Communication

We will communicate with you via your university email and through announcements on iLearn. If you have queries for the unit convenor, you can: 

  • Post your question on the iLearn discussion board (preferred for general queries that may benefit other students)
  • Send a private message to the unit convenor via iLearn

Please check your university email and iLearn regularly to ensure you do not miss important updates.

Technology Used and Required

You are expected to access the unit iLearn site regularly to download required materials (e.g. PDF files) and stay up to date with unit announcements. Important information may also be sent to your student email account, so please check your email frequently to ensure you do not miss any updates.

Unit iLearn Page

The URL of the BMOL6202 Macromolecules iLearn site is: http://ilearn.mq.edu.au/

You will be asked for a username and a password. Your username is your student MQ ID. Your MQ ID and password have been mailed to you by the University. If you have lost them, go to the student portal: http://my.mq.edu.au.

Unit Schedule

S2 Wk Week starting Lecture 1   Lecture 2   Workshop/SGTA sessions Practical (on campus) Assessments Due
14SCO T5 Lecture Theatre 14SCO T4 Lecture Theatre (on campus, see timetable)    
Monday: 10 - 11 a.m Tuesday 9 - 10 a.m Mon 11 - 2 p.m; 01CC 107 Groupwork Learning Space OR Mon 3 - 6 p.m; 01CC 107 Groupwork Learning Space Wed 9-12 pm OR Wed 1-4 pm Held in 14 Sir Christopher Ondaatje Ave - 349 + 350 Labs                              
1 27-Jul Introduction to the Unit (recording on iLearn ONLY) BS Introduction to Topic (recording on iLearn ONLY) BS   -    -    - 
2 3-Aug Chemistry of non-covalent Interactions BS Chemistry of non-covalent Interactions BS   -  Prac 1: Cyclodextrin Host-Guest Chemistry   - 
3 10-Aug Folding & stability of macromolecules in solution BS Folding & stability of macromolecules in solution BS SGTA 1 #WS1: Practical report help session   -    - 
4 17-Aug Folding & stability of macromolecules in solution BS Biological Macromolecules: Carbohydrates - Protein Glycosylation MA   -  Prac 2: Protein Unfolding/Thermodynamics   - 
5 24-Aug Biological Macromolecules: Proteins BS Biological Macromolecules: Proteins BS SGTA 2 #WS2: David Baker nobel prize lecture (and discussion)   -    - 
6 31-Aug Biological Macromolecules: Proteins BS Biomacromolecules: Nucleic acids - DNA Nanotechnology BS   -  Prac 3: Spectroscopic characterisation of amyloid fibril formation by lysozyme   - 
7 7-Sep Special Topic: Molecules built to specific shapes - NanoParticles YW Synthesis & self-assembly AGB SGTA 3 #WS3 Biomolecules workshop Part A    -    - 
8 14-Sep Synthesis & self-assembly AGB Synthesis & self-assembly AGB   Prac 4: Making and characterisation of nanogold particles -
                                                                                    Mid-semester break: 21 September - 5 October, 2026 
9 5-Oct Public holiday - Biomacromolecules: Lipids - Synthetic Lipid biology BS Public Holiday   - Lab Book (40%) - 6 October, 2026 
10 12-Oct Characterising Macromolecules - Scattering methods AGB Characterising Macromolecules - Electron Microscopy AGB SGTA 4 #WS4. Biomolecules workshop Part B   -    - 
11 19-Oct Characterising Macromolecules - Molecular Mass, size and shape (i) BS Characterising Macromolecules - Molecular Mass, size and shape (ii) BS     -   - 
12 26-Oct Characterising Macromolecules - Optical methods BS Characterising Macromolecules - Structural methods (X-ray) BS #WS5: Case studies: Oral Presentations (on campus)   - Case study Oral (20%) - 26 October, 2026
13 2-Nov Characterising Macromolecules - Structural methods (NMR and others) BS Course Summary - Q&A BS   -   -   - 
Lecturer code: BS - Dr Bhumika Shah; MA - A/Prof. Morten Andersen; AGB - A/Prof. Alf Garcia Bennett; YW - Prof. Yuling Wang
***Schedule is subject to change as the semester progresses

 

Policies and Procedures

Macquarie University policies and procedures are accessible from Policy Central (https://policies.mq.edu.au). Students should be aware of the following policies in particular with regard to Learning and Teaching:

Students seeking more policy resources can visit Student Policies (https://students.mq.edu.au/support/study/policies). It is your one-stop-shop for the key policies you need to know about throughout your undergraduate student journey.

To find other policies relating to Teaching and Learning, visit Policy Central (https://policies.mq.edu.au) and use the search tool.

Student Code of Conduct

Macquarie University students have a responsibility to be familiar with the Student Code of Conduct: https://students.mq.edu.au/admin/other-resources/student-conduct

Results

Results published on platform other than eStudent, (eg. iLearn, Coursera etc.) or released directly by your Unit Convenor, are not confirmed as they are subject to final approval by the University. Once approved, final results will be sent to your student email address and will be made available in eStudent. For more information visit connect.mq.edu.au or if you are a Global MBA student contact globalmba.support@mq.edu.au

Academic Integrity

At Macquarie, we believe academic integrity – honesty, respect, trust, responsibility, fairness and courage – is at the core of learning, teaching and research. We recognise that meeting the expectations required to complete your assessments can be challenging. So, we offer you a range of resources and services to help you reach your potential, including free online writing and maths support, academic skills development and wellbeing consultations.

Student Support

Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/

Academic Success

Academic Success provides resources to develop your English language proficiency, academic writing, and communication skills.

The Library provides online and face to face support to help you find and use relevant information resources. 

Student Services and Support

Macquarie University offers a range of Student Support Services including:

Student Enquiries

Got a question? Ask us via the Service Connect Portal, or contact Service Connect.

IT Help

For help with University computer systems and technology, visit https://students.mq.edu.au/support/technology/service-desk

When using the University's IT, you must adhere to the Acceptable Use of IT Resources Policy. The policy applies to all who connect to the MQ network including students.

Changes from Previous Offering

To provide students with more time to focus on learning, understanding, and reflecting on the unit content, the assessment structure was revised in 2025. The unit now comprises three assessments: a Laboratory Book (40%), a Case Study (20%), and a Final Examination (40%).

We value student feedback and use it to continually improve the learning experience. Students are encouraged to provide constructive feedback through the University student surveys, directly to the teaching staff, or via the FSE Student Experience & Feedback link on the iLearn page.

Feedback from the 2025 offering of the unit was overwhelmingly positive. Students appreciated the clarity of the revised assessment requirements and the high level of support provided by the teaching team. One suggestion for improvement was that the assessment due dates were clustered toward the end of the semester. In response, the 2026 offering has been redesigned so that practical classes commence in Week 2, allowing the Laboratory Book assessment to be completed and submitted shortly after the mid-semester break.

Although class participation does not contribute directly to your final grade, all lectures, practicals, and SGTA sessions are designed to support your learning and provide essential knowledge and skills needed to successfully complete the assessments.


Unit information based on version 2026.03 of the Handbook