Students

MEDI2005 – Human Health and Disease Processes

2026 – Session 1, In person-scheduled-weekday, North Ryde

General Information

Download as PDF
Unit convenor and teaching staff Unit convenor and teaching staff Unit Convenor
Dr Esther Lim
Contact via Email
Office 20, Level 1, 75 Talavera Road
Consultation hours: By appointment.
Lecturer
Dr Elena Shklovskaya
Contact via Email
Level 1, 75 Talavera Rd, Macquarie University.
Consultation hours: By appointment.
Course Director
A/Prof. Mark Butlin
Contact via iLearn message
Level 1, 75 Talavera Rd, Macquarie University.
Consultation hours: By appointment.
Credit points Credit points
10
Prerequisites Prerequisites
(50cp at 1000 level or above) and admission to BClinSc
Corequisites Corequisites
Co-badged status Co-badged status
Unit description Unit description

This unit integrates fundamental knowledge of human biological processes to human health and diseases. This unit focuses on key concepts in immunology, microbiology and oncology to further develop your understanding of major human diseases. In this unit, you will learn about fundamental changes in body physiology due to injury and disease, including local and systemic responses, and molecular and cellular adaptations. You will investigate disease aetiology, pathogenesis and processes at the cellular, tissue and body system levels and approach disease from a personal, community and global perspective. You will engage in discussions of disease incidence, prevalence and control, using recent local and global health examples. Learning activities will include lectures, self-directed online learning tasks, lab-based practical, and interactive tutorials and presentations. Through this unit you will gain an understanding of health and disease processes that will be critical for a profession in medicine, healthcare or biomedical research. 

Important Academic Dates

Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates

Learning Outcomes

On successful completion of this unit, you will be able to:

  • ULO1: Apply medical terminology to describe pathological processes, including the body's systemic and local responses to tissue injury, infection and neoplastic transformation. (Capability 1: Scientist and Scholar)
  • ULO2: Explain the multifactorial nature of health and disease by integrating knowledge of host defence mechanisms, immune responses, and genetic and biological factors that contribute to disease. (Capability 2: Practitioner)
  • ULO3: Evaluate factors influencing disease development and transmission, and the role of medical microbiology and epidemiology in infection control and disease prevention. (Capability 3: Engaged Global Citizen)
  • ULO4: Apply scientific knowledge and current research to interpret clinical scenarios and communicate key concepts in health and disease mechanisms. (Capability 4: Practitioner)

General Assessment Information

Grade descriptors and other information concerning grading are contained in the Macquarie University Assessment Policy.

All final grades are determined by a grading committee, in accordance with the Macquarie University Assessment Policy, and are not the sole responsibility of the Unit Convenor.

Students will be awarded a final grade and a mark, which must correspond to the grade descriptors specified in the Assessment Procedure.

To pass this unit, you must demonstrate sufficient evidence of achievement of the learning outcomes, meet any ungraded requirements, and achieve a final mark of 50 or better.

Further details for each assessment task will be available on iLearn.

Late Submissions

Unless a Special Consideration request has been submitted and approved, a 5% penalty (OF THE TOTAL POSSIBLE MARK) will be applied each day a written assessment is not submitted, up to the 7th day (including weekends). After the 7th day, a grade of ‘0’ will be awarded even if the assessment is submitted. Submission time for all written assessments is set at 11.55 pm. A 1-hour grace period is provided to students who experience a technical concern. Submission of assessments after 7 days can be accepted at the discretion of the unit convenor and may be taken into account in determining whether you have met the learning outcomes of the unit to support passing the unit.

 For example:

Number of days (hours) late

Total Possible Marks

Deduction

Raw mark

Final mark

1 day (1-24 hours)

100

5

75

70

2 days (24-48 hours)

100

10

75

65

3 days (48-72 hours)

100

15

75

60

7 days (144-168 hours)

100

35

75

40

>7 days (>168 hours)

100

75

0

For any late submissions of time-sensitive tasks, such as scheduled tests/exams, performance assessments/presentations, and/or scheduled practical assessments/labs, students need to submit an application for Special Consideration. 

Special Consideration

If you are unable to complete an assessment task on or by the specified date due to circumstances that are unexpected, unavoidable, significantly disruptive and beyond your control, you may apply for special consideration in accordance with the Special Consideration Policy. Applications for special consideration must be supported by appropriate evidence and submitted via Service Connect.

Assessment Tasks

Name Weighting Hurdle Due Groupwork/Individual Short Extension AI assisted?
Poster Presentation 30% No Week 8 Individual and Group No Open AI
Practical Test 20% No Week 12 Individual No Observed
End of session examination 50% No Exam timetable Individual No Observed

Poster Presentation

Assessment Type 1: Presentation task
Indicative Time on Task 2: 24 hours
Due: Week 8
Weighting: 30%
Groupwork/Individual: Individual and Group
Short extension 3: No
AI assisted?: Open AI

Development and design of a scientific poster based on group research of an assigned topic, individual presentation of a component of the research topic and engagement with the research posters.   


On successful completion you will be able to:
  • Explain the multifactorial nature of health and disease by integrating knowledge of host defence mechanisms, immune responses, and genetic and biological factors that contribute to disease. (Capability 2: Practitioner)
  • Evaluate factors influencing disease development and transmission, and the role of medical microbiology and epidemiology in infection control and disease prevention. (Capability 3: Engaged Global Citizen)
  • Apply scientific knowledge and current research to interpret clinical scenarios and communicate key concepts in health and disease mechanisms. (Capability 4: Practitioner)

Practical Test

Assessment Type 1: Practice-based task
Indicative Time on Task 2: 14 hours
Due: Week 12
Weighting: 20%
Groupwork/Individual: Individual
Short extension 3: No
AI assisted?: Observed

In-class simulated test assessing practical skills acquired throughout the unit. 


On successful completion you will be able to:
  • Apply medical terminology to describe pathological processes, including the body's systemic and local responses to tissue injury, infection and neoplastic transformation. (Capability 1: Scientist and Scholar)
  • Explain the multifactorial nature of health and disease by integrating knowledge of host defence mechanisms, immune responses, and genetic and biological factors that contribute to disease. (Capability 2: Practitioner)
  • Evaluate factors influencing disease development and transmission, and the role of medical microbiology and epidemiology in infection control and disease prevention. (Capability 3: Engaged Global Citizen)

End of session examination

Assessment Type 1: Examination
Indicative Time on Task 2: 20 hours
Due: Exam timetable
Weighting: 50%
Groupwork/Individual: Individual
Short extension 3: No
AI assisted?: Observed

Formal written exam using a combination of question types assessing content delivered across the session. This task is completed under examination conditions during the University examination period.


On successful completion you will be able to:
  • Apply medical terminology to describe pathological processes, including the body's systemic and local responses to tissue injury, infection and neoplastic transformation. (Capability 1: Scientist and Scholar)
  • Explain the multifactorial nature of health and disease by integrating knowledge of host defence mechanisms, immune responses, and genetic and biological factors that contribute to disease. (Capability 2: Practitioner)
  • Evaluate factors influencing disease development and transmission, and the role of medical microbiology and epidemiology in infection control and disease prevention. (Capability 3: Engaged Global Citizen)
  • Apply scientific knowledge and current research to interpret clinical scenarios and communicate key concepts in health and disease mechanisms. (Capability 4: Practitioner)

1 If you need help with your assignment, please contact:

  • the academic teaching staff in your unit for guidance in understanding or completing this type of assessment
  • the Writing Centre for academic skills support.

2 Indicative time-on-task is an estimate of the time required for completion of the assessment task and is subject to individual variation.

3 An automatic short extension is available for some assessments. Apply through the Service Connect Portal.

Delivery and Resources

As a student enrolled in this unit, you will engage in a range of online and face-to-face learning activities, including readings, online modules, videos, lectures, tutorials, and practicals. Details can be found on the iLearn site for this unit.

Lectures: All lectures are pre-recorded and will be made available on iLearn the Friday prior to the teaching week. Please review the lecture content before attending your tutorial class. 

Tutorials: There are face-to-face on-campus tutorials every week with the exception of Weeks 1, 2, 8 and 13. Please make sure you are enrolled in one of the tutorial class. Tutorial attendance is expected.

Practicals: There are six online practical modules to be completed throughout this unit, released in Weeks 1, 4, 5, 6, 9 and 11. You are expected to complete these practicals at your own pace but it is highly recommended that you complete these by the week that they are released. You also have one face-to-face laboratory practical which you must enroll in and are expected to attend in Week 2. All practical content will be assessed in the on-campus practical exam in Week 12 - please make sure you are enrolled for this class.

Recommended Readings

Please note that these books and the prescribed readings for each week are recommended to complement your understanding of the lecture content. The prescribed readings are not compulsory and will not be assessed unless covered in the lectures.

Pathophysiology: The Biologic Basis for Disease in Adult and Children, Kathryn L. McCance, Sue E. Huether, Valentina L. Brashers, Neal S. Rote, 8th Edition (2019), Elsevier

Mims' Medical Microbiology and Immunology, Richard V. Goering, Hazel M. Dockrell, Mark Zuckerman, Peter L. Chiodini, 6th Edition (2019), Elsevier 

Technology Used

Active participation in the learning activities throughout the unit will require students to have access to a tablet, laptop or similar device. Students who do not own their own laptop computer may borrow one from the university library.

Unit Schedule

Week Lectures Tutorials Practicals Assessments Book Chapter

Week 1

23 February

Introductory lecture

(Dr. Esther Lim)

 

No 

Online practical

  • Language of Pathology
  • Introduction to Medical Terminology 
 

Pathophysiology Chapter 1: Cellular Biology

Week 2

2 March

Basic bacteriology

(Dr. Esther Lim)

No

 

Lab practical  
  • Isolation and identification of bacteria
 

 

Mims' Medical Chapters 2 and 8: The bacteria and The host-parasite relationship 

Pathophysiology Chapter 10: Infection

 

Week 3

9 March

Basic virology

(Dr. Russell Diefenbach)

Yes

 

No

 

 

Mims' Medical Chapter 3: The viruses

Pathophysiology Chapter 10: Infection

 

Week 4

16 March

Introduction to immunology: Altered cellular and tissue biology

(Prof Patrick McNeil)

 

Yes

 

Online practical

 

  • Lymphatic system

 

Formative quiz

 

Pathophysiology Chapter 2: Altered Cellular and Tissue Biology

Week 5

23 March

Inflammation and innate immunity

(Dr. Elena Shklovskaya)

Yes

Online practical  
  • ELISA 
 

Pathophysiology Chapter 7: Innate Immunity

Week 6

30 March

Humoral and cellular responses

(Dr. Elena Shklovskaya

Yes

Online practical  
  • Immunity and vaccination
 

Pathophysiology Chapter 8: Adaptive Immunity 

Week 7

20 April

Alterations in immunity and inflammation

(Dr. Elena Shklovskaya)

Yes

No  

Pathophysiology Chapter 9: Alterations in Immunity and Inflammation 

Week 8

27 April

No Lecture

Poster presentation due

No

No  Poster Presentation (30%)  

Week 9

4 May

Basic hematology

(Dr. Mira Strkalj)

Yes

Online practical

 

  • Interpreting blood test 

 

 

Pathophysiology Chapter 29: Alterations of Erythrocyte, Platelet and Hemostatic Function

Week 10

11 May

Cancer Biology and Hallmarks

(Dr. Esther Lim)

Yes

 

No

 

Pathophysiology Chapter 12: Cancer Biology

Week 11

18 May

Cancer microenvironment and treatments

(Dr. Esther Lim)

Yes

Online practical  
  • Histological features of cancer
 

Pathophysiology Chapter 12: Cancer Biology

Week 12

25 May

Cancer epidemiology

(Dr. Esther Lim)

Yes

No Practical Test (20%)

Pathophysiology Chapter 13: Cancer Epidemiology

Week 13

1 June

 

No Lecture

No  No 

 

Final Exam (50%) - exam timetable

 

Policies and Procedures

Macquarie University policies and procedures are accessible from Policy Central (https://policies.mq.edu.au). Students should be aware of the following policies in particular with regard to Learning and Teaching:

Students seeking more policy resources can visit Student Policies (https://students.mq.edu.au/support/study/policies). It is your one-stop-shop for the key policies you need to know about throughout your undergraduate student journey.

To find other policies relating to Teaching and Learning, visit Policy Central (https://policies.mq.edu.au) and use the search tool.

Student Code of Conduct

Macquarie University students have a responsibility to be familiar with the Student Code of Conduct: https://students.mq.edu.au/admin/other-resources/student-conduct

Results

Results published on platform other than eStudent, (eg. iLearn, Coursera etc.) or released directly by your Unit Convenor, are not confirmed as they are subject to final approval by the University. Once approved, final results will be sent to your student email address and will be made available in eStudent. For more information visit connect.mq.edu.au or if you are a Global MBA student contact globalmba.support@mq.edu.au

Academic Integrity

At Macquarie, we believe academic integrity – honesty, respect, trust, responsibility, fairness and courage – is at the core of learning, teaching and research. We recognise that meeting the expectations required to complete your assessments can be challenging. So, we offer you a range of resources and services to help you reach your potential, including free online writing and maths support, academic skills development and wellbeing consultations.

Student Support

Macquarie University provides a range of support services for students. For details, visit http://students.mq.edu.au/support/

Academic Success

Academic Success provides resources to develop your English language proficiency, academic writing, and communication skills.

The Library provides online and face to face support to help you find and use relevant information resources. 

Student Services and Support

Macquarie University offers a range of Student Support Services including:

Student Enquiries

Got a question? Ask us via the Service Connect Portal, or contact Service Connect.

IT Help

For help with University computer systems and technology, visit http://www.mq.edu.au/about_us/offices_and_units/information_technology/help/

When using the University's IT, you must adhere to the Acceptable Use of IT Resources Policy. The policy applies to all who connect to the MQ network including students.

Artificial Intelligence Tools

Macquarie University recognises that artificial intelligence (AI), especially generative AI, is rapidly reshaping education and the modern workplace. As AI becomes increasingly accessible, the University and your teaching staff are committed to preparing you to use these tools effectively, ethically, and with strong professional judgment. Rather than restricting technology, the emphasis is on helping you understand when and how AI can be used to enhance productivity, support learning, and reflect real-world professional practice. Across your degree, we will support you to develop the critical thinking, adaptability, and values-based decision-making skills required to navigate evolving AI tools responsibly, including acknowledging their use appropriately.  You should always appropriately acknowledge when you have used AI tools within assessment tasks, including which AI tools you have used and how you have used them.

To provide clarity, Macquarie University uses a simple, two-tiered approach to AI in assessment:

  • AI Open assessments allow you to fully incorporate AI, reflecting authentic tasks where AI would normally be used in professional settings.
  • Observed with AI Optional assessments involve tasks where you either demonstrate essential knowledge without technology or show how you apply AI under supervision.

Across both categories, the goal is to ensure you build foundational knowledge, exercise sound judgment, and engage with AI in ways that uphold ethical, cultural, and university values.

Inclusion and Diversity

Social inclusion at Macquarie University is about giving everyone who has the potential to benefit from higher education the opportunity to study at university, participate in campus life and flourish in their chosen field. The University has made significant moves to promote an equitable, diverse and exciting campus community for the benefit of staff and students. It is your responsibility to contribute towards the development of an inclusive culture and practice in the areas of learning and teaching, research, and service orientation and delivery. As a member of the Macquarie University community, you must not discriminate against or harass others based on their sex, gender, race, marital status, carers' responsibilities, disability, sexual orientation, age, political conviction or religious belief. All staff and students are expected to display appropriate behaviour that is conducive to a healthy learning environment for everyone.

Professionalism

In the Faculty of Medicine, Health and Human Sciences, professionalism is a key capability embedded in all our courses.

As part of developing professionalism, students are expected to attend all small group interactive sessions, including clinical, practical, laboratory, work-integrated learning (e.g., PACE placements), and team-based learning activities. Some learning activities are recorded (e.g., face-to-face lectures), however you are encouraged to avoid relying upon such material as they do not recreate the whole learning experience and technical issues can and do occur. As an adult learner, we respect your decision to choose how you engage with your learning, but we would remind you that the learning opportunities we create for you have been done so to enable your success, and that by not engaging you may impact your ability to successfully complete this unit. We equally expect that you show respect for the academic staff who have worked hard to develop meaningful activities and prioritise your learning by communicating with them in advance if you are unable to attend a small group interactive session.

Another dimension of professionalism is having respect for your peers. It is the right of every student to learn in an environment that is free of disruption and distraction. Please arrive to all learning activities on time, and if you are unavoidably detained, please join activity as quietly as possible to minimise disruption. Phones and other electronic devices that produce noise and other distractions must be turned off prior to entering class. Where your own device (e.g., laptop) is being used for class-related activities, you are asked to close down all other applications to avoid distraction to you and others. Please treat your fellow students with the utmost respect. If you are uncomfortable participating in any specific activity, please let the relevant academic know.

Changes since First Published

Date Description
03/02/2026 "By appointment" in unit contacts given context with "Consultation hours: By appointment."

Unit information based on version 2026.02 of the Handbook