| Unit convenor and teaching staff |
Unit convenor and teaching staff
Paul Haynes
Jessica Boomer
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|---|---|
| Credit points |
Credit points
10
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| Prerequisites |
Prerequisites
Admission to GradDipRes or GradCertRes or (BMOL6202 and BMOL6201 and Admission to GradDipBiotech or MBiotech)
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| Corequisites |
Corequisites
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| Co-badged status |
Co-badged status
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| Unit description |
Unit description
This unit outlines molecular principles underlying developments in protein science and research. As well as detailing separation technologies, the course addresses structural biology, protein analysis and bioinformatics. Practices common in the biotechnology and pharmaceutical industries to isolate recombinant proteins are emphasized. Protein purification and analysis methods are introduced and discussed in detail. Molecular properties leading to the 3D shape of proteins are explored, using a range of computer modelling techniques.
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Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates
On successful completion of this unit, you will be able to:
To pass this unit you need to: Achieve a total mark equal to or greater than 50% across all assessments.
We strongly encourage all students to actively participate in all learning activities. Regular engagement is crucial for your success in this unit, as these activities provide opportunities to deepen your understanding of the material, collaborate with peers, and receive valuable feedback from instructors, to assist in completing the unit assessments. Your active participation not only enhances your own learning experience but also contributes to a vibrant and dynamic learning environment for everyone.
Late Submission Policy
Need help? Review the Special Consideration page HERE
Assessments where Late Submissions will be accepted
Special Consideration Policy
The Special Consideration Policy aims to support students who have been impacted by short-term circumstances or events that are serious, unavoidable and significantly disruptive, and which may affect their performance in assessment.
Descriptions of Assessment Activities and other information
| Name | Weighting | Hurdle | Due | Groupwork/Individual | Short Extension | AI Approach |
|---|---|---|---|---|---|---|
| Pet Protein Purification Project | 40% | No | 07/06/2026 | Individual | Yes | Open |
| Final exam | 40% | No | Examination Period | Individual | No | Observed |
| Practical report | 20% | No | 04/05/2026 | Individual | Yes | Open |
Assessment Type 1: Portfolio
Indicative Time on Task 2: 35 hours
Due: 07/06/2026
Weighting: 40%
Groupwork/Individual: Individual
Short extension 3: Yes
AI Approach: Open
Each student will be assigned a 'pet protein' of biochemical or medical importance as a case study throughout this Unit. The project includes making and presenting a real-life 3-D physical model of the protein structure.
Assessment Type 1: Examination
Indicative Time on Task 2: 35 hours
Due: Examination Period
Weighting: 40%
Groupwork/Individual: Individual
Short extension 3: No
AI Approach: Observed
An invigilated formal examination covering all aspects of the scientific content of the unit.
Assessment Type 1: Written Submission
Indicative Time on Task 2: 17 hours
Due: 04/05/2026
Weighting: 20%
Groupwork/Individual: Individual
Short extension 3: Yes
AI Approach: Open
Students will complete a protein purification activity and write a report including the techniques used and the results achieved.
1 If you need help with your assignment, please contact:
2 Indicative time-on-task is an estimate of the time required for completion of the assessment task and is subject to individual variation.
3 An automatic short extension is available for some assessments. Apply through the Service Connect Portal.
Class scheduling
Lectures and Workshops both begin in week 1 of semester. Weekly lectures will be delivered in person, with recordings made available via iLearn for revision purposes. Weekly workshops will be held in person, and will include worksheets and other activities to reinforce the learning of the lecture content.
Lectures: 2 hrs Wednesdays 12-2pm 14SCO T5 .
Workshops: 1 hr Wednesday 3pm – 4pm 01CC 214
Our practical class will be held in the 14ER 130/150 laboratories during semester break, Tuesday 14th of April to Thursday 16th of April.
Methods of Communication
The unit convenor will communicate mainly via Discussion Forum and Announcements on the iLearn site, and also via emails to students MQ email addresses. Personal email addresses must not be used.
Lectures 2 hrs, Wednesdays 12-2 14SCO T5; Workshops 1 hr, Wednesdays 3-4 01CC 214; Practical class April 14-16th 14ER 130/150.
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Week |
Date |
Lecture Topic |
Workshop Subject |
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1 |
Feb 25 |
1 - Introduction to Protein Structure 2 - Protein functional groups |
primary sequence and structure of proteins Pet Protein Allocation |
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2 |
Mar4 |
3 - Isolating proteins 4 - protein staining |
Database information (20 min) and quiz 1 (not assessed, lectures 1-4, 10 questions) |
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3 |
Mar 11 |
5 – Protein purification I 6 – Protein purification II |
protein purification worksheet |
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4 |
Mar 18 |
7-8 Protein crystallography (Bhumika Shah) |
Protein crystallography
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5 |
Mar 25 |
9-10 Protein NMR (Rob Willows) |
protein NMR |
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6 |
April 1 |
11-12 Cryo EM (Rob Willows) |
Quiz no 2 – (not assessed, 20 questions, functional groups, isolation and purification, NMR, crystallography, cryo EM. |
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Apr 8 |
Midsem break week 1 |
Midsem break week 1 |
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Apr 15 |
Practical Class Apr 14-16 |
Midsem break week 2 |
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7 |
Apr 22 |
13 – Folding domains and motifs 14 – Membrane proteins |
folds, topologies and crystallography worksheet |
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8 |
Apr 29 |
15 – Protein folding 16 – Protein secondary structures |
molecular graphics using Pymol. Working with the program and completing an assessable worksheet. |
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9 |
May 6 |
17 - Protein dynamics 18 - bioinformatics |
protein folding, folds and domains worksheet
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10 |
May 13 |
19 – UV and CD spectra 20 - Spectroscopic methods |
CD worksheet questions. Revision and class demo of alphafold |
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11 |
May 20 |
21 - Mass spectrometry 22 - Glycomics |
Quiz no 3 (folding, structures, domains, motifs, membranes, dynamics, bioinformatics, UV and CD spectra, mass spectrometry, glycomics, not assessable, 20 questions) |
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12 |
May 27 |
Pet protein presentations |
Pet protein presentations |
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13 |
Jun 3 |
Pet proteins (reserved if needed) |
Pet protein presentations (reserved) |
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Lecture contents have been revised and updated to keep up with the latest developments in the field. Although no marks are associated with attendance, all activities provide students with key content designed to help them understand the content and complete the assessments.
We value student feedback to be able to continually improve the way we offer our units. As such we encourage students to provide constructive feedback via student surveys, to the teaching staff directly, or via the FSE Student Experience & Feedback link in the iLearn page. Student feedback from the previous offering of this unit was strongly positive overall, with students pleased with the clarity around assessment requirements and the level of support from teaching staff. We will continue to strive to improve the level of support and the level of student engagement.
| Date | Description |
|---|---|
| 23/03/2026 | Date format updated |
Unit information based on version 2026.01R of the Handbook