| Unit convenor and teaching staff |
Unit convenor and teaching staff
Unit Convenor
David Raftos
Contact via david.raftos@mq.edu.au
Other Staff
Vince Repaci
Contact via vincenzo.repaci@mq.edu.au
|
|---|---|
| Credit points |
Credit points
3
|
| Prerequisites |
Prerequisites
(12cp in 200- or 300-level BIOL units) or admission to GradCertBiotech
|
| Corequisites |
Corequisites
|
| Co-badged status |
Co-badged status
|
| Unit description |
Unit description
This unit studies the relationship between infectious micro-organisms, and the animals and plants that they infect. The unit also focuses on the effects of environment change on the ability of organisms to cope with disease. It begins by investigating the ecology of disease and the way it moulds the immune systems of plants and animals. We then describe the basic paradigms used by plants and animals to detect the presence of infectious agents and activate immune responses against them. The unit ends by discussing the key methods used by different organisms to kill pathogens and overcome infection. Throughout the unit we focus on systems that have direct relevance to medicine, agriculture or aquaculture, highlighting new discoveries that are changing the face of modem immunology.
|
Information about important academic dates including deadlines for withdrawing from units are available at https://www.mq.edu.au/study/calendar-of-dates
On successful completion of this unit, you will be able to:
| Name | Weighting | Due | Groupwork/Individual | Short Extension | AI Approach |
|---|---|---|---|---|---|
| Final examination | 50% | Exam Period | No | ||
| Midsemester test | 10% | Int: 12/9, Ext: 24/9 | No | ||
| Practical reports | 15% | Int: Weekly, Ext: 3/9, 8/10 | No | ||
| Seminar | 10% | Int: weeks 9 & 10, Ext: 26/9 | No | ||
| Literature review | 15% | Oct 29 | No |
Due: Exam Period
Weighting: 50%
Groupwork/Individual:
Short extension 3: No
AI Approach:
Due: Int: 12/9, Ext: 24/9
Weighting: 10%
Groupwork/Individual:
Short extension 3: No
AI Approach:
Midsemester test will be comprised of multiple choice questions that are designed to assess your understanding in terms of both lecture material and practical classes.
Due: Int: Weekly, Ext: 3/9, 8/10
Weighting: 15%
Groupwork/Individual:
Short extension 3: No
AI Approach:
You will be required to answer a series of questions based on each practical. Answers to these questions must be submitted in the week following the practical.
Due: Int: weeks 9 & 10, Ext: 26/9
Weighting: 10%
Groupwork/Individual:
Short extension 3: No
AI Approach:
Groups of four students will prepare and present a short (20 minute) seminar on a selected topic.
Due: Oct 29
Weighting: 15%
Groupwork/Individual:
Short extension 3: No
AI Approach:
You will need to write a 2,000 word (excluding references and figures) literature review on the topic of your tutorial seminar
Classes
· There are two weekly one hour lectures (C5A 226 Tutorial Rm, 12pm Wed and 8am Fri) and weekly 3 hour practical sessions (E8A150, 1pm – 4pm Mon OR 9am – 12pm Tues). The timetable for classes can be found on the University web site at: https://timetables.mq.edu.au/2012/showtimetable.aspx
· Practical content will be covered during two on campus sessions for external students:
Sat 25th and Sun 26th August from 9:00am until 4:00pm
and Mon 24th to Wed 26th Sept from 9:00am until 4:00pm
·
Attendance at practical sessions is a compulsory component of this unit.
Required and Recommended texts and/or materials
When reading this textbook, you should remember that Biol367 takes a different approach to teaching immunobiology, and so does not refer to concepts such as "innate" and "adaptive" immunity. So if there are apparent contradictions in the textbook, always refer back to the lectures as a guide. The textbook provides access to the Elsevier Evolve Learning website, which provides additional material such as animations of key processes.
· Lecture graphics will be available online on the unit website (via iLearn) prior to each lecture. There are 20 lectures in Biol367 covering the major topics of recognition, induction and effect. Each lecture has a series of learning objectives described in terms of Key Topics on the second slide of each lecture Powerpoint file. You will need to understand each of these key topics. The lecture graphics mainly use images from the textbook and from primary research articles and reviews. The written text on the graphics is kept to a minimum and you will need to fill in the gaps with your own notes from the lectures and, where necessary, from the textbook. The lecture series does not cover topics in the order in which they are presented in the textbook so that graphics for a single lecture may come from different chapters of the textbook.
Unit web page
· This unit operates as an online unit via iLearn. The website will contain lecture and practical class notes, and will be updated regularly with additional information and announcements. We encourage you to visit the website frequently to check for updates.
| WEEK | LECTURE | PRACTICAL |
| 1 |
1. Introduction to unit 2. Summary of an immune response: recognition, induction and effect |
None |
| 2 |
3. Self and not-self: why do animals and plants needs immune systems? 4. Pathogens, parasites, competitors and symbionts |
Introduction to practical classes |
| 3 |
5. Antigens and PAMPs: What defines not-self? 6. Am I me, or not them? Recognition paradigms in plants and animals |
1. Pattern recognition |
| 4 |
7. Pattern recognition molecules: lectins and Toll-like receptors 8. Hypervariable recognition molecules I: New immune response gene families of invertebrates and plants |
2. Antibody structure |
| 5 |
9. Hypervariable recognition molecules II: Antibodies and t-cell receptors 10. Danger, anti-viral states and inflammation |
3. Phagolysomal defence I |
| 6 |
11. Intracellular antigens, antigen processing and presentation 12. Activation of T-cells by processed antigens |
4. Phagolysomal defence II |
| 7 |
Mid semester test No lecture |
5. Proteolytic effector cascades I: Phenoloxidase |
|
Mid semester test |
||
| 8 |
13. Signalling, clonal selection and memory 14. Autoreactivity and education: To thine own self be true |
No practical classes |
| 9 |
15. Plant defence I: R genes and AVR genes – the gene-for-gene model 16. Plant defence II: systemic acquired resistance |
Seminars |
| 10 |
17. Effector cascades: complement and phenoloxidase 18. Antimicrobial proteins |
Seminars |
| 11 |
19. The phagolysosomal system 20. Synthesis |
6. Proteolytic effector cascades II: Complement |
| 12 |
No lectures |
7. Clinical Immunology: The Immunology of Pregnancy |
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Academic Honesty Policy http://www.mq.edu.au/policy/docs/academic_honesty/policy.html
Assessment Policy http://www.mq.edu.au/policy/docs/assessment/policy.html
Grade Appeal Policy http://www.mq.edu.au/policy/docs/gradeappeal/policy.html
Special Consideration Policy http://www.mq.edu.au/policy/docs/special_consideration/policy.html
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